DNA methylation is an epigenetic mechanism regulating gene expression. Changes in DNA
methylation were suggested to be useful biomarkers for diagnosis, and for the determination …

The advent of iPSCs has brought about a significant transformation in stem cell research,
opening up promising avenues for advancing cancer treatment. The formation of cancer is a …

Objective This study aimed to determine the effects of diet‐induced paternal obesity on
cognitive function in mice offspring. Methods Male mice (F0) were randomized to receive …

In 2023, colorectal cancer (CRC) is the third most diagnosed malignancy and the third
leading cause of cancer death worldwide. At the time of the initial visit, 20% of patients …

Aim: To develop a reduced representation bisulfite sequencing (RRBS) approach for rapid
and affordable genome-wide DNA methylation analysis. Methods: We have selected …

ATP-binding cassette (ABC) transporters, such as breast cancer resistance protein (BCRP),
are key players in resistance to multiple anti-cancer drugs, leading to cancer treatment …

Taking into account recently obtained data indicating the participation of circulating
extracellular DNA (exDNA) in tumorigenesis, enzymes with deoxyribonucleic activity have …

A priority in solving the problem of drug resistance is to understand the molecular
mechanism of how a drug induces the resistance response within cells. Because many …

Understanding how organisms cope with global change is a major question in many fields of
biology. Mainly, understanding the molecular mechanisms supporting rapid phenotypic …

Background Airborne particulate matter (PM), a complex mixture of organic and inorganic
compounds, is a major public health concern due to its adverse health effects …