Degenerative disorders of joints, especially osteoarthritis (OA), result in persistent pain and
disability and high costs to society. Nevertheless, the molecular mechanisms of OA have not …

Endocytosis mediates the cellular uptake of micronutrients and cell surface proteins. Clathrin-
mediated endocytosis (CME) is the housekeeping pathway in resting cells but additional …

Simple Summary Breast cancer is considered the second most occurring cancer after lung
cancer globally. The treatment for breast cancer includes surgery, radiation, chemotherapy …

Globally, most cases of gastroenteritis are caused by pandemic GII. 4 human norovirus
(HuNoV) strains with no approved therapies or vaccines available. The cellular pathways …

Central nervous system (CNS) homeostasis critically depends on the interaction between
neurons and glia cells. Extracellular vesicles (EVs) recently emerged as versatile …

The plasma membrane tension strongly affects cell surface processes, such as migration,
endocytosis and signalling. However, it is not known whether the membrane tension of …

Cholera toxin B-subunit (CTxB) has emerged as one of the most widely utilized tools in
membrane biology and biophysics. CTxB is a homopentameric stable protein that binds …

Breast cancer continues to pose a substantial worldwide health concern, demanding a
thorough comprehension of the complex interaction between cancerous cells and the …

A review of our current knowledge of B cell antigen uptake mechanisms, the relevance of
these processes to pathology, and outstanding questions in the field. Specific antigens …

Drug delivery vectors are widely applied to increase drug efficacy while reducing the side
effects and potential toxicity of a drug. They allow for patient-tailored therapy, dose titration …