Cannabidiol (CBD) is one of the main pharmacologically active phytocannabinoids of
Cannabis sativa L. CBD is non-psychoactive but exerts a number of beneficial …

It is well known that certain active ingredients of the plants of Cannabis genus, ie, the
“phytocannabinoids”[pCBs; eg,(−)-trans-Δ9-tetrahydrocannabinol (THC),(−)-cannabidiol …

The therapeutic potential of Cannabis sativa has been recognized since ancient times.
Phytocannabinoids, endocannabinoids and synthetic cannabinoids activate two major G …

Background Neuroinflammation plays a vital role in Alzheimer's disease and other
neurodegenerative conditions. Microglia are the resident mononuclear immune cells of the …

Bone is a dynamic tissue, whose homeostasis is maintained by a fine balance between
osteoclast (OC) and osteoblast (OB) activity. The endocannabinoid/endovanilloid (EC/EV) …

Introduction: Muscle wasting in Duchenne Muscular Dystrophy is caused by myofiber
fragility and poor regeneration that lead to chronic inflammation and muscle replacement by …

Simple Summary Alzheimer's disease (AD) is a complex, multifactorial disease where
numerous components, such as environment, lifestyle, comorbidities, and genetic …

The classical cannabinoid receptors CB1 and CB2 as well as the cannabinoid-sensitive
receptor GPR55 are widely distributed throughout the mammalian body. In the …

Cannabinoids include the active constituents of Cannabis or are molecules that mimic the
structure and/or function of these Cannabis-derived molecules. Cannabinoids produce …

One important risk factor for the development of asthma is allergen sensitization. Recent
increasing evidence suggests a prominent role of mast cells in asthma pathophysiology …