Updating the striatal–pallidal wiring diagram

LZ Fang, MC Creed - Nature neuroscience, 2024 - nature.com
The striatal and pallidal complexes are basal ganglia structures that orchestrate learning
and execution of flexible behavior. Models of how the basal ganglia subserve these …

Learning of food preferences: mechanisms and implications for obesity & metabolic diseases

HR Berthoud, CD Morrison, K Ackroff… - International Journal of …, 2021 - nature.com
Omnivores, including rodents and humans, compose their diets from a wide variety of
potential foods. Beyond the guidance of a few basic orosensory biases such as attraction to …

Dorsal hippocampus to nucleus accumbens projections drive reinforcement via activation of accumbal dynorphin neurons

KM Ibrahim, N Massaly, HJ Yoon, R Sandoval… - Nature …, 2024 - nature.com
The hippocampus is pivotal in integrating emotional processing, learning, memory, and
reward-related behaviors. The dorsal hippocampus (dHPC) is particularly crucial for …

Cocaine-induced projection-specific and cell type-specific adaptations in the nucleus accumbens

AK Zinsmaier, Y Dong, YH Huang - Molecular psychiatry, 2022 - nature.com
Cocaine craving, seeking, and relapse are mediated, in part, by cocaine-induced adaptive
changes in the brain reward circuits. The nucleus accumbens (NAc) integrates and …

Input-specific modulation of murine nucleus accumbens differentially regulates hedonic feeding

DJ Christoffel, JJ Walsh, BD Heifets, P Hoerbelt… - Nature …, 2021 - nature.com
Hedonic feeding is driven by the “pleasure” derived from consuming palatable food and
occurs in the absence of metabolic need. It plays a critical role in the excessive feeding that …

Roles for the gut microbiota in regulating neuronal feeding circuits

BY Kristie, EY Hsiao - The Journal of clinical investigation, 2021 - Am Soc Clin Investig
The gut microbiota has the capacity to affect host appetite via intestinal satiety pathways, as
well as complex feeding behaviors. In this Review, we highlight recent evidence that the gut …

Behavioral and neural dissociation of social anxiety and loneliness

J Lieberz, SG Shamay-Tsoory, N Saporta… - Journal of …, 2022 - Soc Neuroscience
Loneliness is a public health concern with detrimental effects on physical and mental well-
being. Given phenotypical overlaps between loneliness and social anxiety (SA), cognitive …

The nucleus accumbens shell: a neural hub at the interface of homeostatic and hedonic feeding

AM Marinescu, MA Labouesse - Frontiers in Neuroscience, 2024 - frontiersin.org
Feeding behavior is a complex physiological process regulated by the interplay between
homeostatic and hedonic feeding circuits. Among the neural structures involved, the nucleus …

Microbes, oxytocin and stress: converging players regulating eating behavior

C Cuesta‐Marti, F Uhlig, B Muguerza… - Journal of …, 2023 - Wiley Online Library
Oxytocin is a peptide‐hormone extensively studied for its multifaceted biological functions
and has recently gained attention for its role in eating behavior, through its action as an …

[HTML][HTML] Linking external stimuli with internal drives: A role for the ventral hippocampus

VS Turner, RO O'Sullivan, MA Kheirbek - Current opinion in neurobiology, 2022 - Elsevier
The ventral hippocampus (vHPC) has long been thought of as the “emotional” hippocampus.
Over the past several years, the complexity of vHPC has come to light, highlighting the …