Parathyroid hormone and its related peptides in bone metabolism
T Chen, Y Wang, Z Hao, Y Hu, J Li - Biochemical pharmacology, 2021 - Elsevier
Parathyroid hormone (PTH) is an 84-amino-acid peptide hormone that is secreted by the
parathyroid gland. It has different administration modes in bone tissue through which it …
parathyroid gland. It has different administration modes in bone tissue through which it …
The role of integrin family in bone metabolism and tumor bone metastasis
L Mao, L Wang, J Xu, J Zou - Cell Death Discovery, 2023 - nature.com
Integrins have been the research focus of cell-extracellular matrix adhesion (ECM) and
cytokine receptor signal transduction. They are involved in the regulation of bone …
cytokine receptor signal transduction. They are involved in the regulation of bone …
[HTML][HTML] Matrix-bound Cyr61/CCN1 is required to retain the properties of the bone marrow mesenchymal stem cell niche but is depleted with aging
M Marinkovic, Q Dai, AO Gonzalez, ON Tran, TJ Block… - Matrix Biology, 2022 - Elsevier
Previously, we showed that extracellular matrices (ECMs), produced ex vivo by various
types of stromal cells, direct bone marrow mesenchymal stem cells (BM-MSCs) in a tissue …
types of stromal cells, direct bone marrow mesenchymal stem cells (BM-MSCs) in a tissue …
Sclareol inhibits RANKL-induced osteoclastogenesis and promotes osteoblastogenesis through promoting CCN1 expression via repressing the MAPK pathway
X Li, Y Wang, L Li, S Zhou, F Zhao - Cell Biology and Toxicology, 2021 - Springer
Osteoclasts are crucial cellular components of bone and are the cause of various bone
problems like osteoporosis. Various biological activities such as anti-tumorous, anti …
problems like osteoporosis. Various biological activities such as anti-tumorous, anti …
Single‐Cell Transcriptomic Analysis Reveals Biomechanical Loading‐Induced Imbalance in Bone and Fat, Leading to Ossification in Lumbar Intervertebral Disc …
P Zhang, Y Wang, J Bai, J Zhang… - Journal of Cellular …, 2025 - Wiley Online Library
In this study, we explored the impact of different biomechanical loadings on lumbar spine
motion segments, particularly concerning intervertebral disc degeneration (IVDD). We aimed …
motion segments, particularly concerning intervertebral disc degeneration (IVDD). We aimed …
CCN1 expression is regulated by mechanical stimuli in tendons
Tendon overuse injuries are common, but the processes that govern tendon response to
mechanical load are not fully understood. A series of experiments of in vitro and in vivo …
mechanical load are not fully understood. A series of experiments of in vitro and in vivo …
[HTML][HTML] Cyr61 delivery promotes angiogenesis during bone fracture repair
Compromised vascular supply and insufficient neovascularization impede bone repair,
increasing risk of non-union. Cyr61, Cysteine-rich angiogenic inducer of 61kD (also known …
increasing risk of non-union. Cyr61, Cysteine-rich angiogenic inducer of 61kD (also known …
Adipose-PAS interactions in the context of its localised bio-engineering potential
M Nohawica, A Errachid… - Biomedical …, 2021 - spandidos-publications.com
Adipocytes are a known source of stem cells. They are easy to harvest, and are a suitable
candidate for autogenous grafts. Adipose derived stem cells (ADSCs) have multiple target …
candidate for autogenous grafts. Adipose derived stem cells (ADSCs) have multiple target …
Rbm15 mediated m6A RNA modification participates in the regulation of AKAP2 on chondrogenesis
K Peng, Y Dai, X Lv, P Li, G Lv, B Wang, Y Li - 2023 - researchsquare.com
Purpose: To investigate the function of AKAP2 in the pathogenesis of AIS by regulating the
growth of chondrocyte and explore the mechanism involved. Methods: ATDC-5 cells was …
growth of chondrocyte and explore the mechanism involved. Methods: ATDC-5 cells was …