Answering the question as to why we age is tantamount to answering the question of what is
life itself. There are countless theories as to why and how we age, but, until recently, the very …

Age is the single greatest risk factor for a wide range of diseases, and as the mean age of
human populations grows steadily older, the impact of this risk factor grows as well …

Social Work with the Aged and Their Families presents the functional-age model (FAM) of
intergenerational treatment, an integrative theoretical framework for social workers …

The field of aging research has progressed rapidly over the past few decades. Genetic
modulators of aging rate that are conserved over a broad evolutionary distance have now …

One of the greatest challenges in biology is to improve the understanding of the
mechanisms which underpin aging and how these affect health. The need to better …

Aim During ageing, advanced glycation end-products (AGEs) accumulate in extracellular
matrix proteins like collagen and contribute to a decline in organ function. As skin …

Aging is a leading cause of human morbidity and mortality, but efforts to slow or reverse its
effects are hampered by an incomplete understanding of its multi-faceted origins. Systems …

Aging research is undergoing a paradigm shift, which has led to new and innovative
methods of exploring this complex phenomenon. The systems biology approach endeavors …

A routine approach to inferring functions for a gene set is by using function enrichment
analysis based on GO, KEGG or other curated terms and pathways. However, such analysis …

The underlying cellular mechanisms that characterize aging are complex and multifaceted.
However, it is emerging that aging could be regulated by two distinct metabolic hubs. These …