Clinical trials based on mesenchymal stromal cells are exponentially increasing: where are we in recent years?

U Galderisi, G Peluso, G Di Bernardo - Stem cell reviews and reports, 2022 - Springer
Mesenchymal stromal cells (MSCs), present in the stromal component of several tissues,
include multipotent stem cells, progenitors, and differentiated cells. MSCs have quickly …

A review on curability of cancers: more efforts for novel therapeutic options are needed

S Wang, Y Liu, Y Feng, J Zhang, J Swinnen, Y Li, Y Ni - Cancers, 2019 - mdpi.com
Cancer remains a major cause of death globally. Given its relapsing and fatal features,
curing cancer seems to be something hardly possible for the majority of patients. In view of …

Stem-cell transplantation in children with acute lymphoblastic leukemia: a prospective international multicenter trial comparing sibling donors with matched unrelated …

C Peters, M Schrappe, A von Stackelberg… - Journal of clinical …, 2015 - ascopubs.org
Purpose Although hematopoietic stem-cell transplantation is widely performed in children
with high-risk acute lymphoblastic leukemia (ALL), the influence of donor types is poorly …

A pragmatic multi-institutional approach to understanding transplant-associated thrombotic microangiopathy after stem cell transplant

CE Dandoy, S Rotz, PB Alonso, A Klunk… - Blood …, 2021 - ashpublications.org
Transplant-associated thrombotic microangiopathy (TA-TMA) is a severe complication of
hematopoietic stem cell transplantation (HSCT). A single-center prospective screening study …

Clinical use of mesenchymal stromal cells in the treatment of acute graft-versus-host disease

S Elgaz, Z Kuçi, S Kuçi, H Bönig, P Bader - Transfusion Medicine and …, 2019 - karger.com
Acute graft-versus-host disease (aGvHD) continues to impact morbidity and mortality after
allogeneic stem cell transplantation (allo-SCT). First-line therapy for aGvHD still remains the …

[HTML][HTML] Down syndrome and leukemia: insights into leukemogenesis and translational targets

MK Mateos, D Barbaric, SA Byatt, R Sutton… - Translational …, 2015 - ncbi.nlm.nih.gov
Children with Down syndrome (DS) have a significantly increased risk of childhood
leukemia, in particular acute megakaryoblastic leukemia (AMKL) and acute lymphoblastic …

Mesenchymal stem cells: a promising way in therapies of graft-versus-host disease

X Zhou, N Jin, F Wang, B Chen - Cancer Cell International, 2020 - Springer
It is well acknowledged that allogeneic hematopoietic stem cell transplantation (allo-HSCT)
is an effective treatment for numerous malignant blood diseases, which has also been …

Gut microbiota diversity before allogeneic hematopoietic stem cell transplantation as a predictor of mortality in children

R Masetti, D Leardini, E Muratore, M Fabbrini… - Blood, 2023 - ashpublications.org
The correlation existing between gut microbiota diversity and survival after allogeneic
hematopoietic stem cell transplantation (allo-HSCT) has so far been studied in adults …

Hematopoietic stem-cell transplantation does not improve the poor outcome of children with hypodiploid acute lymphoblastic leukemia: A report from Children's …

JL McNeer, M Devidas, Y Dai, AJ Carroll… - Journal of Clinical …, 2019 - ascopubs.org
Purpose Children and young adults with hypodiploid B-lymphoblastic leukemia (B-ALL) fare
poorly and hematopoietic stem-cell transplantation (HSCT) is often pursued in first complete …

Persistent MRD before and after allogeneic BMT predicts relapse in children with acute lymphoblastic leukaemia

R Sutton, PJ Shaw, NC Venn, T Law… - British Journal of …, 2015 - Wiley Online Library
Minimal residual disease (MRD) during early chemotherapy is a powerful predictor of
relapse in acute lymphoblastic leukaemia (ALL) and is used in children to determine …