Flavonoid production: current trends in plant metabolic engineering and de novo microbial production

H Tariq, S Asif, A Andleeb, C Hano, BH Abbasi - Metabolites, 2023 - mdpi.com
Flavonoids are secondary metabolites that represent a heterogeneous family of plant
polyphenolic compounds. Recent research has determined that the health benefits of fruits …

Naturally occurring prenylated chalcones from plants: Structural diversity, distribution, activities and biosynthesis

K Zhou, S Yang, SM Li - Natural Product Reports, 2021 - pubs.rsc.org
Covering: up to July 2020 Naturally occurring chalcones carrying up to three modified or
unmodified C5-, C10-, and C15-prenyl moieties on both rings A and B as well as at the α …

A straightforward access to trifluoromethylated natural products through late-stage functionalization

HP Li, XH He, C Peng, JL Li, B Han - Natural Product Reports, 2023 - pubs.rsc.org
Covering: 2011 to 2021 Trifluoromethyl (CF3)-modified natural products have attracted
increasing interest due to their magical effect in binding affinity and/or drug metabolism and …

Immunomodulatory potential of flavonoids for the treatment of autoimmune diseases and tumour

L Han, Q Fu, C Deng, L Luo, T Xiang… - … Journal of Immunology, 2022 - Wiley Online Library
The immune system plays an indispensable role in maintaining human health against the
invasion of foreign materials, microorgainisms and pathogens. The autoimmune diseases …

Biosynthesis of 3-hydroxyphloretin using rational design of 4-hydroxyphenylacetate 3-monooxygenase

S Xu, P Zheng, P Sun, P Chen… - Journal of Agricultural and …, 2023 - ACS Publications
The compound 3-hydroxyphloretin is a typical dihydrochalcone that can be obtained in
plants by the 3-hydroxylation of phloretin. Here, the flavin-dependent two-component …

Dihydrochalcones: Methods of acquisition and pharmacological properties—A first systematic review

M Stompor, D Broda, A Bajek-Bil - Molecules, 2019 - mdpi.com
Dihydrochalcones are a class of secondary metabolites, for which demand in biological and
pharmacological applications is still growing. They posses several health-endorsing …

Pour some sugar on me: The diverse functions of phenylpropanoid glycosylation

A de Barros Rates, I Cesarino - Journal of Plant Physiology, 2023 - Elsevier
The phenylpropanoid metabolism is the source of a vast array of specialized metabolites
that play diverse functions in plant growth and development and contribute to all aspects of …

Alterations of Phenylpropanoid Biosynthesis Lead to the Natural Formation of Pinkish-Skinned and White-Fleshed Strawberry (Fragaria × ananassa)

L Jiang, M Yue, Y Liu, Y Ye, Y Zhang, Y Lin… - International Journal of …, 2022 - mdpi.com
Anthocyanin content is important for both the external and internal fruit quality of cultivated
strawberries, but the mechanism of its accumulation in pinkish-skinned and white-fleshed …

Effect of pre-harvest treatments with salicylic and methyl salicylic acid on the chemical profile and activity of some phenylpropanoid pathway related enzymes in apple …

S Gacnik, R Veberic, S Marinovic, H Halbwirth… - Scientia …, 2021 - Elsevier
The effects of single and multiple sprayings with salicylic acid (SA) and methyl-salicylic acid
(MeSA) on the composition of phenolic compounds in apple leaves of the'Topaz'cultivar …

Effects of natural dihydrochalcones in sweet tea (Lithocarpus polystachyus) on diabetes: a systematical review and meta-analysis of animal studies

XM Chen, WQ Yang, X Wang, C Chen, ZM Qian… - Food & Function, 2022 - pubs.rsc.org
Sweet tea (Lithocarpus polystachyus Rehd.), a natural functional food highly rich in
dihydrochalcones including trilobatin, phlorizin and phloretin, is reported to possess …