Cytokine-induced memory-like NK cells: from the basics to clinical applications
I Terrén, A Orrantia, G Astarloa-Pando… - Frontiers in …, 2022 - frontiersin.org
Natural killer (NK) cells are lymphocytes with a key role in the defense against viral
infections and tumor cells. Although NK cells are classified as innate lymphoid cells (ILCs) …
infections and tumor cells. Although NK cells are classified as innate lymphoid cells (ILCs) …
Progress and applications of mass cytometry in sketching immune landscapes
T Zhang, AR Warden, Y Li… - Clinical and Translational …, 2020 - Wiley Online Library
Recently emerged mass cytometry (cytometry by time‐of‐flight [CyTOF]) technology permits
the identification and quantification of inherently diverse cellular systems, and the …
the identification and quantification of inherently diverse cellular systems, and the …
Metabolic changes of Interleukin-12/15/18-stimulated human NK cells
I Terrén, A Orrantia, A Mosteiro, J Vitallé… - Scientific Reports, 2021 - nature.com
Natural Killer (NK) cells acquire memory-like properties following a brief stimulation with IL-
12, IL-15 and IL-18. These IL-12/15/18-preactivated NK cells, also known as cytokine …
12, IL-15 and IL-18. These IL-12/15/18-preactivated NK cells, also known as cytokine …
CD56-negative NK cells: Frequency in peripheral blood, expansion during HIV-1 infection, functional capacity, and KIR expression
ATH Cocker, F Liu, Z Djaoud, LA Guethlein… - Frontiers in …, 2022 - frontiersin.org
Human NK cells are usually defined as CD3-CD56+ lymphocytes. However, a CD56-CD16+
(CD56neg) lymphocyte population that displays NK-associated markers expands during …
(CD56neg) lymphocyte population that displays NK-associated markers expands during …
Charge-altering releasable transporters enable phenotypic manipulation of natural killer cells for cancer immunotherapy
AJ Wilk, NLB Weidenbacher, R Vergara… - Blood …, 2020 - ashpublications.org
Chimeric antigen receptor (CAR) natural killer (NK) cells are an emerging cell therapy with
promising results in oncology trials. However, primary human NK cells are difficult to …
promising results in oncology trials. However, primary human NK cells are difficult to …
TIGIT is upregulated by HIV-1 infection and marks a highly functional adaptive and mature subset of natural killer cells
Objective: Our objective was to investigate the mechanisms that govern natural killer (NK)-
cell responses to HIV, with a focus on specific receptor--ligand interactions involved in HIV …
cell responses to HIV, with a focus on specific receptor--ligand interactions involved in HIV …
Implication of interleukin-12/15/18 and ruxolitinib in the phenotype, proliferation, and polyfunctionality of human cytokine-preactivated natural killer cells
I Terrén, I Mikelez, I Odriozola, A Gredilla… - Frontiers in …, 2018 - frontiersin.org
A brief in vitro stimulation of natural killer (NK) cells with interleukin (IL)-12, IL-15, and IL-18
endow them a memory-like behavior, characterized by higher effector responses when they …
endow them a memory-like behavior, characterized by higher effector responses when they …
Contribution of natural killer cells in innate immunity against colorectal cancer
Natural killer cells are members of the innate immune system and promote cytotoxic activity
against tumor or infected cells independently from MHC recognition. NK cells are modulated …
against tumor or infected cells independently from MHC recognition. NK cells are modulated …
Diversification of human NK cells: Lessons from deep profiling
NK cells are innate lymphocytes with important roles in immunoregulation,
immunosurveillance, and cytokine production. Originally defined on the functional basis of …
immunosurveillance, and cytokine production. Originally defined on the functional basis of …
Enhanced expression of natural cytotoxicity receptors on cytokine-induced memory-like natural killer cells correlates with effector function
S Carreira-Santos, N López-Sejas… - Frontiers in …, 2023 - frontiersin.org
Introduction Natural killer (NK) cells are a key component of the innate immune system,
involved in defending the host against virus-infected cells and tumor immunosurveillance …
involved in defending the host against virus-infected cells and tumor immunosurveillance …