Dental tissue infection and disease result in acute and chronic activation of the innate
immune response, which is mediated by molecular and cellular signaling. Different cell …

Autophagy, a metabolic pathway that plays an important role in maintaining the dynamic
balance of cells, has two types, ie non-selective autophagy and selective autophagy. The …

The nervous system maintains physiological homeostasis through reflex pathways that
modulate organ function. This process begins when changes in the internal milieu (eg …

Although vitamin D deficiency is a common feature among patients presenting with active
tuberculosis, the full scope of vitamin D action during Mycobacterium tuberculosis (Mtb) …

Research efforts on nanomaterial-based therapies for the treatment of autoimmune diseases
and cancer have spiked and have made rapid progress over the past years. Nanomedicine …

Abstract Purinergic 2X7 receptor (P2X7R) and nucleotide‑binding oligomerization domain-
like receptor protein 3 (NLRP3) are expressed in macrophages in atherosclerotic lesions …

Preeclampsia (PE) is a specific syndrome of pregnancy, characterized by hypertension and
proteinuria. This pathology is associated with hyperuricemia and elevated serum levels of …

The NOD-like receptor family, pyrin domain containing 3 (NLRP3) inflammasome, a
multiprotein complex, triggers caspase-1 activation and maturation of the proinflammatory …

The inflammasome is a multi-protein complex that induces maturation of inflammatory
cytokines interleukin (IL)-1β and IL-18 through activation of caspase-1. Several nucleotide …

Inflammation is a part of the body's immune response for protection against pathogenic
infections and other cellular damages; however, chronic inflammation is a major cause of …