[HTML][HTML] Immune defence to invasive fungal infections: A comprehensive review

B Pathakumari, G Liang, W Liu - Biomedicine & Pharmacotherapy, 2020 - Elsevier
The fungal infections are relatively common in humans that can range from common, mild
superficial infections to life-threatening invasive infections. Most of the pathogenic fungi are …

[HTML][HTML] Current antifungal drugs and immunotherapeutic approaches as promising strategies to treatment of fungal diseases

S Nami, A Aghebati-Maleki, H Morovati… - Biomedicine & …, 2019 - Elsevier
Invasive candidiasis (IC) can affect individuals with various underlying diseases hospitalized
in different parts of hospitals. In recent decades, IC has caused 27–55% mortality in general …

[HTML][HTML] Fungal vaccines, mechanism of actions and immunology: A comprehensive review

S Nami, R Mohammadi, M Vakili, K Khezripour… - Biomedicine & …, 2019 - Elsevier
Fungal infections include a wide range of opportunistic and invasive diseases. Two of four
major fatal diseases in patients with human immunodeficiency virus (HIV) infection are …

Interferon-gamma as adjunctive immunotherapy for invasive fungal infections: a case series

CE Delsing, MS Gresnigt, J Leentjens, F Preijers… - BMC infectious …, 2014 - Springer
Background Invasive fungal infections are very severe infections associated with high
mortality rates, despite the availability of new classes of antifungal agents. Based on …

Inflammatory monocytes orchestrate innate antifungal immunity in the lung

V Espinosa, A Jhingran, O Dutta, S Kasahara… - PLoS …, 2014 - journals.plos.org
Aspergillus fumigatus is an environmental fungus that causes invasive aspergillosis (IA) in
immunocompromised patients. Although-CC-chemokine receptor-2 (CCR2) and Ly6C …

Superficial Dermatophytosis across the World's Populations: Potential Benefits from Nanocarrier-Based Therapies and Rising Challenges

P Keshwania, N Kaur, J Chauhan, G Sharma… - ACS …, 2023 - ACS Publications
The most prevalent infection in the world is dermatophytosis, which is a major issue with
high recurrence and can affect the entire body including the skin, hair, and nails. The major …

Harnessing the immune response to fungal pathogens for vaccine development

A Rivera, J Lodge, C Xue - Annual review of microbiology, 2022 - annualreviews.org
Invasive fungal infections are emerging diseases that kill over 1.5 million people per year
worldwide. With the increase of immunocompromised populations, the incidence of invasive …

TLR3 essentially promotes protective class I–restricted memory CD8+ T-cell responses to Aspergillus fumigatus in hematopoietic transplanted patients

A Carvalho, A De Luca, S Bozza… - Blood, The Journal …, 2012 - ashpublications.org
Aspergillus fumigatus is a model fungal pathogen and a common cause of severe infections
and diseases. CD8+ T cells are present in the human and murine T-cell repertoire to the …

Immunity to fungi

S LeibundGut-Landmann, M Wüthrich… - Current opinion in …, 2012 - Elsevier
The global increase in fungal disease burden, the emergence of novel pathogenic fungi,
and the lack of fungal vaccines have focused intense interest in elucidating immune defense …

Concentration-dependent protein loading of extracellular vesicles released by Histoplasma capsulatum after antibody treatment and its modulatory action upon …

LM Baltazar, D Zamith-Miranda, MC Burnet, H Choi… - Scientific reports, 2018 - nature.com
Diverse pathogenic fungi secrete extracellular vesicles (EV) that contain macromolecules,
including virulence factors that can modulate the host immune response. We recently …