Review on porous materials for the thermal stabilization of proteins

NA Montoya, RE Roth, EK Funk, P Gao… - Microporous and …, 2022 - Elsevier
Proteins, the key components of vaccines, enzymes and many types of therapeutics, are
sensitive to denaturing and loss of structure when exposed to high temperatures. One way to …

Investigating BioCaRGOS, a Sol–Gel Matrix for the Stability of Heme Proteins under Enzymatic Degradation and Low pH

CS Potnis, CA Grapperhaus, G Gupta - ACS omega, 2023 - ACS Publications
There have been significant advances in the development of vaccines for the prevention of
various infectious diseases in the last few decades. These vaccines are mainly composed of …

Long term storage of miRNA at room and elevated temperatures in a silica sol–gel matrix

R Chauhan, TS Kalbfleisch, CS Potnis, M Bansal… - RSC …, 2021 - pubs.rsc.org
Storage of biospecimens in their near native environment at room temperature can have a
transformative global impact, however, this remains an arduous challenge to date due to the …

Protein Thermal Stabilization and Delivery via Adsorption onto Porous Silicas

NM Oyuela - 2022 - search.proquest.com
The cold chain is a problem that affects the whole pharmaceutical industry: in 2019, 45% of
new FDA approved drugs required refrigeration or freezing. It is estimated that biopharma …