Skeletal disorders are among the leading debilitating factors affecting millions of people
worldwide. The use of stem cells for tissue repair has raised many promises in various …

Spinal cord injury (SCI) is a devastating neurological disorder that affects thousands of
individuals each year. Over the past decades an enormous progress has been made in our …

Scar formation is an intractable medical problem that appears after skin wounds have
healed. Recent research has shown that exosomes secreted by human adipose …

Mesenchymal stem/stromal cells (MSCs) comprise a heterogeneous population of cells with
multilineage differentiation potential, the ability to modulate oxidative stress, and secrete …

Human umbilical cord (UC) is a promising source of mesenchymal stem cells (MSCs). Apart
from their prominent advantages, such as a painless collection procedure and faster self …

Stem-cell-mediated bone repair has been used in clinical trials for the regeneration of large
craniomaxillofacial defects, to slow the process of bone degeneration in patients with …

Stem cells have two features: the ability to differentiate along different lineages and the
ability of self-renewal. Two major types of stem cells have been described, namely …

Cutaneous wound repair is a highly coordinated cascade of cellular responses to injury
which restores the epidermal integrity and its barrier functions. Even under optimal healing …

The effective delivery of target-specific siRNA to the brain by exploiting the exosomes
derived from dendritic cells renders the paradigm shift for the prospective use of nanosized …

To investigate the therapeutic mechanism of action of transplanted stem cells and develop
exosome-based nanotherapeutics for ischemic stroke, we assessed the effect of exosomes …