Photobiocatalytic strategies for organic synthesis

MA Emmanuel, SG Bender, C Bilodeau… - Chemical …, 2023 - ACS Publications
Biocatalysis has revolutionized chemical synthesis, providing sustainable methods for
preparing various organic molecules. In enzyme-mediated organic synthesis, most reactions …

Enzymatic reductions for the chemist

F Hollmann, IWCE Arends, D Holtmann - Green Chemistry, 2011 - pubs.rsc.org
When challenged by a difficult reduction reaction, a chemist should always also consider
biocatalysis in synthesis planning. The inherent selectivity of enzymes has been known for …

Enantioselective enzymatic desymmetrizations in organic synthesis

E García-Urdiales, I Alfonso, V Gotor - Chemical Reviews, 2005 - ACS Publications
During the recent past years, tremendous efforts have been made to establish
enantioselective routes for the preparation of enantiomerically pure compounds due to their …

Biocatalysis for synthesis of pharmaceuticals

RN Patel - Bioorganic & medicinal chemistry, 2018 - Elsevier
Chirality is a key factor in the safety and efficacy of many drug products and thus the
production of single enantiomers of drug intermediates and drugs has become important …

Biocatalytic reductions and chemical versatility of the old yellow enzyme family of flavoprotein oxidoreductases

HS Toogood, JM Gardiner, NS Scrutton - ChemCatChem, 2010 - Wiley Online Library
The old yellow enzyme (OYE) family is a large group of flavin‐dependent redox biocatalysts
with major applications in the industrial reduction of activated alkenes. These enzymes have …

Jasmonates: structural requirements for lipid-derived signals active in plant stress responses and development

C Wasternack, E Kombrink - ACS Chemical Biology, 2010 - ACS Publications
Jasmonates are lipid-derived signals that mediate plant stress responses and development
processes. Enzymes participating in biosynthesis of jasmonic acid (JA)(1, 2) and …

[PDF][PDF] How Green is Biocatalysis? To Calculate is To Know.

Y Ni, D Holtmann, F Hollmann - ChemCatChem, 2014 - researchgate.net
Green chemistry aims to minimize the environmental hazards of chemical processes and
their products. Ever since its introduction by Anastas,[1] this principle has inspired …

Biocatalytic redox reactions for organic synthesis: nonconventional regeneration methods

F Hollmann, IWCE Arends, K Buehler - ChemCatChem, 2010 - Wiley Online Library
Redox enzymes have tremendous potential as catalysts for preparative organic chemistry.
Their usually high selectivity, paired with their catalytic efficiency under mild reaction …

Enantioenriched compounds via enzyme-catalyzed redox reactions

M Hall, AS Bommarius - Chemical reviews, 2011 - ACS Publications
Redox reactions are essential to any currently known form of life and are at the core of a
majority of metabolic processes, such as cellular respiration or photosynthesis. As about …

Mimicking Nature: Synthetic Nicotinamide Cofactors for C C Bioreduction Using Enoate Reductases

CE Paul, S Gargiulo, DJ Opperman, I Lavandera… - Organic …, 2013 - ACS Publications
A series of synthetic nicotinamide cofactors were synthesized to replace natural
nicotinamide cofactors and promote enoate reductase (ER) catalyzed reactions without …