When challenged by a difficult reduction reaction, a chemist should always also consider biocatalysis in synthesis planning. The inherent selectivity of enzymes has been known for …
E García-Urdiales, I Alfonso, V Gotor - Chemical Reviews, 2005 - ACS Publications
During the recent past years, tremendous efforts have been made to establish enantioselective routes for the preparation of enantiomerically pure compounds due to their …
Chirality is a key factor in the safety and efficacy of many drug products and thus the production of single enantiomers of drug intermediates and drugs has become important …
The old yellow enzyme (OYE) family is a large group of flavin‐dependent redox biocatalysts with major applications in the industrial reduction of activated alkenes. These enzymes have …
C Wasternack, E Kombrink - ACS Chemical Biology, 2010 - ACS Publications
Jasmonates are lipid-derived signals that mediate plant stress responses and development processes. Enzymes participating in biosynthesis of jasmonic acid (JA)(1, 2) and …
Green chemistry aims to minimize the environmental hazards of chemical processes and their products. Ever since its introduction by Anastas,[1] this principle has inspired …
Redox enzymes have tremendous potential as catalysts for preparative organic chemistry. Their usually high selectivity, paired with their catalytic efficiency under mild reaction …
Redox reactions are essential to any currently known form of life and are at the core of a majority of metabolic processes, such as cellular respiration or photosynthesis. As about …
A series of synthetic nicotinamide cofactors were synthesized to replace natural nicotinamide cofactors and promote enoate reductase (ER) catalyzed reactions without …