The role of biomaterials in peripheral nerve and spinal cord injury: a review

B Kaplan, S Levenberg - International journal of molecular sciences, 2022 - mdpi.com
Peripheral nerve and spinal cord injuries are potentially devastating traumatic conditions
with major consequences for patients' lives. Severe cases of these conditions are currently …

Stem cells therapy for spinal cord injury

M Gazdic, V Volarevic, CR Harrell… - International journal of …, 2018 - mdpi.com
Spinal cord injury (SCI), a serious public health issue, most likely occurs in previously
healthy young adults. Current therapeutic strategies for SCI includes surgical …

Commercial scale manufacturing of allogeneic cell therapy

GM Pigeau, E Csaszar, A Dulgar-Tulloch - Frontiers in medicine, 2018 - frontiersin.org
Allogeneic cell therapy products are generating encouraging clinical and pre-clinical results.
Pluripotent stem cell (PSC) derived therapies, in particular, have substantial momentum and …

Human mesenchymal stem cells modulate inflammatory cytokines after spinal cord injury in rat

L Machová Urdzíková, J Růžička, M LaBagnara… - International journal of …, 2014 - mdpi.com
Transplantation of mesenchymal stem cells (MSC) improves functional recovery in
experimental models of spinal cord injury (SCI); however, the mechanisms underlying this …

The future of the patient-specific Body-on-a-chip

A Williamson, S Singh, U Fernekorn, A Schober - Lab on a Chip, 2013 - pubs.rsc.org
As significant advancements in technology focused on Organ-on-a-chip continue, it is
feasible to consider the future of Body-on-a-chip technology. With serious work being done …

Stem cell transplantation: a promising therapy for spinal cord injury

Z Gong, K Xia, A Xu, C Yu, C Wang… - Current Stem Cell …, 2020 - ingentaconnect.com
Spinal Cord Injury (SCI) causes irreversible functional loss of the affected population. The
incidence of SCI keeps increasing, resulting in huge burden on the society. The …

Biomaterials used in stem cell therapy for spinal cord injury

A Higuchi, SS Kumar, G Benelli, QD Ling, HF Li… - Progress in Materials …, 2019 - Elsevier
Spinal cord injury (SCI) is a common, severe damage to the central nervous system. Here,
we discuss the use of biomaterials for stem cell transplantation in preclinical and clinical …

Recent progress in the regeneration of spinal cord injuries by induced pluripotent stem cells

M Csobonyeiova, S Polak, R Zamborsky… - International Journal of …, 2019 - mdpi.com
Regeneration of injuries occurring in the central nervous system, particularly spinal cord
injuries (SCIs), is extremely difficult. The complex pathological events following a SCI often …

[HTML][HTML] Human embryonic stem cells in the treatment of patients with spinal cord injury

G Shroff, R Gupta - Annals of Neurosciences, 2015 - ncbi.nlm.nih.gov
Background Spinal cord injury (SCI) is a neurological condition which paralyses the patient
below the level of injury and could occur due to damage, infection and tumors. Presently …

Concise review: Spinal cord injuries: how could adult mesenchymal and neural crest stem cells take up the challenge?

V Neirinckx, D Cantinieaux, C Coste, B Rogister… - Stem …, 2014 - academic.oup.com
Since several years, adult/perinatal mesenchymal and neural crest stem cells have been
widely used to help experimental animal to recover from spinal cord injury. More …