Filamentous fungi constitute a large group of eukaryotic microorganisms that grow by
forming simple tube-like hyphae that are capable of differentiating into more-complex …

Septins are conserved guanine nucleotide-binding proteins that polymerize into filaments at
the cell cortex or in association with other cytoskeletal proteins, such as actin or …

In order to fully understand any complex biochemical system from a mechanistic point of
view, it is necessary to have access to the three-dimensional structures of the molecular …

Most human cells require anchorage for survival. Cell–substrate adhesion activates diverse
signalling pathways, without which cells undergo anoikis—a form of programmed cell death …

Cells change shape in response to diverse environmental and developmental conditions,
creating topologies with micron-scale features. Although individual proteins can sense …

Many aspects of cytoskeletal assembly and dynamics can be recapitulated in vitro; yet, how
the cytoskeleton integrates signals in vivo across cellular membranes is far less understood …

Fungi have the capacity to cause devastating diseases of both plants and animals, causing
significant harvest losses that threaten food security and human mycoses with high mortality …

Septins are cytoskeletal filaments that assemble at the inner face of the plasma membrane.
They are localized at constriction sites and impact membrane remodeling. We report in vitro …

Septins are GTP binding proteins considered to be novel components of the cytoskeleton.
They polymerize into filaments based on hexameric or octameric core particles in which two …

Septins are GTP-binding proteins that form filaments and higher-order structures on the cell
cortex of eukaryotic cells and associate with actin and microtubule cytoskeletal networks …