One of the most prominent features of tumor cells is uncontrolled cell proliferation caused by
an abnormal cell cycle, and the abnormal expression of cell cycle-related proteins gives …

Cancers remain a major public health problem worldwide, which still require profound
research in both the basic and preclinical fields. Patient-derived xenograft (PDX) models are …

Lack of appropriate models that recapitulate the complexity and heterogeneity of urological
tumours precludes most of the preclinical reagents that target urological tumours from …

Patient‐derived xenografts (PDX) involve transplanting patient cells or tissues into
immunodeficient mice, offering superior disease models compared with cell line xenografts …

The ability of a patient tumor to engraft an immunodeficient mouse is the strongest known
independent indicator of poor prognosis in early-stage non–small cell lung cancer (NSCLC) …

The application of immune checkpoint inhibitors (ICIs) in non-small cell lung cancer has
significantly improved patient survival. However, most patients fail to respond to ICIs or …

Cancer prognosis will benefit from a scoring system that could grade malignant traits of
patient‐derived cells by assessing their growth and metastasis in a living system. Specific …

Lung cancer is one of the most prevalent, fatal, and highly heterogeneous diseases that,
seriously threaten human health. Lung cancer is primarily caused by the aberrant …

The evolving paradigm of the molecular classification of bladder cancer requires models that
represent the classifications with less heterogeneity. Robust transcriptome based molecular …

Identification of tumor antigens and immune subtypes of hepatocellular carcinoma for mRNA
vaccine development - PMC Back to Top Skip to main content NIH NLM Logo Access keys …