Impact of particle size and polydispersity index on the clinical applications of lipidic nanocarrier systems

M Danaei, M Dehghankhold, S Ataei… - Pharmaceutics, 2018 - mdpi.com
Lipid-based drug delivery systems, or lipidic carriers, are being extensively employed to
enhance the bioavailability of poorly-soluble drugs. They have the ability to incorporate both …

Harnessing inhaled nanoparticles to overcome the pulmonary barrier for respiratory disease therapy

Z Jin, Q Gao, K Wu, J Ouyang, W Guo… - Advanced Drug Delivery …, 2023 - Elsevier
The lack of effective treatments for pulmonary diseases presents a significant global health
burden, primarily due to the challenges posed by the pulmonary barrier that hinders drug …

Curcumin encapsulation in functional PLGA nanoparticles: A promising strategy for cancer therapies

F da Silva Feltrin, T Agner, C Sayer… - Advances in colloid and …, 2022 - Elsevier
Nanoparticles have emerged as promising drug delivery systems for the treatment of several
diseases. Novel cancer therapies have exploited these particles as alternative adjuvant …

[HTML][HTML] Nanomedicine for acute respiratory distress syndrome: the latest application, targeting strategy, and rational design

Q Qiao, X Liu, T Yang, K Cui, L Kong, C Yang… - … Pharmaceutica Sinica B, 2021 - Elsevier
Acute respiratory distress syndrome (ARDS) is characterized by the severe inflammation
and destruction of the lung air–blood barrier, leading to irreversible and substantial …

Inorganic nanoparticles as scaffolds for bioorthogonal catalysts

CM Hirschbiegel, X Zhang, R Huang, YA Cicek… - Advanced drug delivery …, 2023 - Elsevier
Bioorthogonal transition metal catalysts (TMCs) transform therapeutically inactive molecules
(pro-drugs) into active drug compounds. Inorganic nanoscaffolds protect and solubilize …

Antimicrobial peptides and nanotechnology, recent advances and challenges

LS Biswaro, MG da Costa Sousa… - Frontiers in …, 2018 - frontiersin.org
Antimicrobial peptides are sequences of amino acids, which present activity against
microorganisms. These peptides were discovered over 70 years ago, and are abundant in …

Nanotechnology-empowered vaccine delivery for enhancing CD8+ T cells-mediated cellular immunity

G Liu, M Zhu, X Zhao, G Nie - Advanced drug delivery reviews, 2021 - Elsevier
After centuries of development, using vaccination to stimulate immunity has become an
effective method for prevention and treatment of a variety of diseases including infective …

An overview of nanotechnologies for drug delivery to the brain

A Ayub, S Wettig - Pharmaceutics, 2022 - mdpi.com
Drug delivery to the brain has been one of the toughest challenges researchers have faced
to develop effective treatments for brain diseases. Owing to the blood–brain barrier (BBB) …

Chitosan-based oral colon-specific delivery systems for polyphenols: recent advances and emerging trends

S Chen, H Zhu, Y Luo - Journal of Materials Chemistry B, 2022 - pubs.rsc.org
Oral colon-targeted delivery systems (OCDSs) have attracted great attention in the delivery
of active compounds targeted to the colon for the treatment of colon and non-colon diseases …

Facile synthesis of metformin loaded Mn3O4-HAp magnetic hydroxyapatite nanocomposites for T1-magnetic resonance imaging guided targeted chemo-phototherapy …

A Mushtaq, X Ma, J Farheen, X Lin, M Tayyab… - Colloids and Surfaces A …, 2023 - Elsevier
Magnetic hydroxyapatite nanocomposites are promising candidates for various biomedical
applications. However, the uncontrolled growth with the unfavorable size limits their …