Currently approved COVID-19 vaccines administered parenterally induce robust systemic
humoral and cellular responses. While highly effective against severe disease, there is …

Monoclonal therapeutic antibodies have revolutionized the treatment of cancer and other
diseases. Fc engineering aims to enhance the effector functions or half-life of therapeutic …

Background As a debilitating condition that can impact a whole spectrum of people and
involve multi-organ systems, long COVID has aroused the most attention than ever …

Abstract Ever-evolving SARS-CoV-2 variants of concern (VOCs) have diminished the
effectiveness of therapeutic antibodies and vaccines. Developing a coronavirus vaccine that …

A growing body of evidence shows that fragment crystallizable (Fc)-dependent antibody
effector functions play an important role in protection from severe acute respiratory …

Understanding mucosal antibody responses from SARS-CoV-2 infection and/or vaccination
is crucial to develop strategies for longer term immunity, especially against emerging viral …

Drug-resistant Pseudomonas aeruginosa (PA) poses an emerging threat to human health
with urgent need for alternative therapeutic approaches. Here, we deciphered the B cell and …

The global rollout of COVID-19 vaccines has played a critical role in reducing pandemic
spread, disease severity, hospitalizations, and deaths. However, the first-generation …

Background To inform future preventive measures including repeated vaccinations, we have
searched for a clinically useful immune correlate of protection against fatal COVID-19 …

The objective of this review was to examine the latest literature regarding the effectiveness
of monoclonal antibodies as COVID-19 prophylaxis therapy for immunocompromised patient …