Pain is one of the most significant causes of suffering and disability world-wide, and
arguably the most burdensome global health challenge. The growing number of patients …

Venomous animals including cone snails, spiders, scorpions, anemones, and snakes have
evolved a myriad of components in their venoms that target the opening and/or closing of …

Venom-derived peptide modulators of ion channel gating are regarded as essential tools for
understanding the molecular motions that occur during the opening and closing of ion …

Chronic pain is a major medical issue which reduces the quality of life of millions and inflicts
a significant burden on health authorities worldwide. Currently, management of chronic pain …

Alpha-neurotoxins target voltage-gated sodium channels (Navs) and constitute an important
component in the venom of Buthidae scorpions. These toxins are short polypeptides highly …

Aim: To determine the presence of voltage-gated K+(Kv) channels in bone marrow-derived
human mesenchymal stem cells (hMSCs) and their impact on differentiation of hMSCs into …

Tarantula spiders, Theraphosidae family, are spread throughout most tropical regions of the
world. Despite their size and reputation, there are few reports of accidents. However, like …

The K+ channel encoded by the Ether-á-go-go-Related Gene (ERG) is expressed in
different tissues of different animal species. There are at least three subtypes of this channel …

A new monotypic genus of Theraphosidae is described from Colombia: Aguapanela Perafán
& Cifuentes gen. nov. with only the type species Aguapanela arvi Perafán, Cifuentes & …

Tarantula venom glands produce a large variety of bioactive peptides. Here we present the
identification of venom components obtained by sequencing clones isolated from a cDNA …