MicroRNAs are small double-stranded RNAs, which negatively regulate gene expression
and have been shown to have key roles in both chondrocyte development and cartilage …

Micro ribonucleic acid (microRNA) regulation and expression has become an emerging field
in determining the mechanisms regulating a variety of inflammation-mediated diseases …

Primary osteoarthritis (OA) is associated with aging, while post‐traumatic OA (PTOA) is
associated with mechanical injury and inflammation. It is not clear whether the two types of …

Objectives. In China, Oldenlandia diffusa (OD) is a natural herb that is widely used and has
been proven to be effective in the treatment of rheumatoid arthritis (RA). This study aimed to …

Non-coding RNAs (ncRNAs) have evolved in eukaryotes as epigenetic regulators of gene
expression. The most abundant regulatory ncRNAs are the 20–24 nt small microRNAs …

Mechanical stress plays an important role in the initiation and progression of osteoarthritis.
Studies show that excessive mechanical stress can directly damage the cartilage …

Osteoarthritis is the most common degenerative joint disorder. MicroRNAs are gene
expression regulators that act post-transcriptionally to control tissue homeostasis. Microarray …

Although virtually all gene networks are predicted to be controlled by miRNAs, the
contribution of this important layer of gene regulation to tissue homeostasis in adult animals …

Exosomes, as lipid nanostructure, are secreted by approximately all cell types within the
body and actively involved in either short or long distances cell–cell communication in an …

Osteoarthritis (OA) is a debilitating degenerative disease of the articular cartilage with a
multifactorial etiology. Aging, the main risk factor for OA development, is associated with a …