This review aims to serve as an introduction to the solute carrier proteins (SLC) superfamily
of transporter proteins and their roles in human cells. The SLC superfamily currently …

The SLC12 family encodes electroneutral cation-coupled chloride cotransporters that are
critical for several physiological processes including cell volume regulation, modulation of …

A hallmark of high-grade cancers is the ability of malignant cells to invade unaffected tissue
and spread disease. This is particularly apparent in gliomas, the most common and lethal …

During the progression of epithelial cancer, cells usually lose epithelial characteristic
features and gain a mesenchymal phenotype. Cervical cancer is a common female …

Zinc is essential for many physiological functions, with a major role in digestive system, skin
health, and learning and memory. On the cellular level, zinc is involved in cell proliferation …

Expression of the zinc receptor, ZnR/GPR39, is increased in higher grade breast cancer
tumors and cells. Zinc, its ligand, is accumulated at larger concentrations in the tumor tissue …

A hallmark of high-grade cancers is the ability of malignant cells to invade unaffected tissue
and spread disease. This is particularly apparent in gliomas, the most common and lethal …

The K+: Cl− cotransporter (KCC) activity is modulated by phosphorylation/
dephosphorylation processes. In isotonic conditions, KCCs are inactive and phosphorylated …

Abstract Background Altered expression of Solute Carrier Family 12 Member 7 (SLC12A7) is
implicated to promote malignant behavior in multiple cancer types through an incompletely …

The objectives of the present study were to investigate the role of K–Cl cotransporter 3
(KCC3) in the regulation of cellular invasion and the clinicopathological significance of its …