MYC in liver cancer: mechanisms and targeted therapy opportunities

F Liu, Z Liao, Z Zhang - Oncogene, 2023 - nature.com
MYC, a major oncogenic transcription factor, regulates target genes involved in various
pathways such as cell proliferation, metabolism and immune evasion, playing a critical role …

Transcription Factors in Prostate Cancer: Insights for Disease Development and Diagnostic and Therapeutic Approaches

KCS Silva, N Tambwe, DH Mahfouz, M Wium… - Genes, 2024 - mdpi.com
Transcription factors (TFs) are proteins essential for the regulation of gene expression, and
they regulate the genes involved in different cellular processes, such as proliferation …

Disruption of spatial proximities among charged groups in equilibrium-denatured states of proteins tracked using protein charge transfer spectra

A Priyadarshi, HM Devi, R Swaminathan - Biochemistry, 2023 - ACS Publications
The absorption and luminescence originating from protein charge transfer spectra
(ProCharTS) depend on the proximity between multiple charged groups in a protein. This …

DispHred: A server to predict pH-dependent order–disorder transitions in intrinsically disordered proteins

J Santos, V Iglesias, C Pintado… - International journal of …, 2020 - mdpi.com
The natively unfolded nature of intrinsically disordered proteins (IDPs) relies on several
physicochemical principles, of which the balance between a low sequence hydrophobicity …

Protein expression/secretion boost by a novel unique 21-mer cis-regulatory motif (Exin21) via mRNA stabilization

Y Zhu, AS Saribas, J Liu, Y Lin, B Bodnar, R Zhao… - Molecular Therapy, 2023 - cell.com
Boosting protein production is invaluable in both industrial and academic applications. We
discovered a novel expression-increasing 21-mer cis-regulatory motif (Exin21) that inserts …

Cold atmospheric plasma driven self-assembly in serum proteins: insights into the protein aggregation to biomaterials

RR Khanikar, P Kalita, M Narzary, D Basumatary… - RSC …, 2022 - pubs.rsc.org
The self-assembly of proteins is crucial in many biomedical applications. This work deals
with understanding the role of cold atmospheric plasma (CAP) on the self-assembly of two …

Label-Free Tracking of Hepatitis B Virus Core Protein Capsid Assembly in Real-Time Using Protein Charge Transfer Spectra

SE Alom, K Swaminathan, V Nuzelu, A Singh… - …, 2024 - ACS Publications
Hepatitis B virions are double-shelled particles, with a diameter of 40–42 nm, consisting of a
nucleocapsid called the HBV core protein (HBV Cp). It is an ordered assembly of 90–120 …

Маркеры апоптоза и пролиферации клеток при воспалительно-фибропролиферативных заболеваниях сосудистой стенки (обзор)

ЭА Климентова, ИА Сучков, АА Егоров… - Современные …, 2020 - cyberleninka.ru
Апоптоз является основным признаком воспалительно-фибропролиферативных
нарушений сосудистой стенки. Исследования на моделях животных показали, что …

Detection of SARS-CoV-2 in COVID-19 Patient Nasal Swab Samples Using Signal Processing

M Al Ahmad, LJA Olule, M Meetani… - IEEE Journal of …, 2021 - ieeexplore.ieee.org
This work presents an opto-electrical method that measures the viral nucleocapsid protein
and anti-N antibody interactions to differentiate between SARS-CoV-2 negative and positive …

Apoptosis and cell proliferation markers in inflammatory-fibroproliferative diseases of the vessel wall

EA Klimentova, IA Suchkov, AA Egorov… - Современные …, 2020 - cyberleninka.ru
Apoptosis is the main feature of inflammatory-fibroproliferative disorders of the vessel wall.
Studies in animal models have shown that smooth muscle cells (SMCs) cultured from …