History of Corneal Cross-Linking

F Hafezi, S Kling, NL Hafezi, ME Aydemir, NJ Lu… - Progress in Retinal and …, 2024 - Elsevier
Corneal cross-linking (CXL) has profoundly changed the management of keratoconus and
other ectatic corneal diseases. Introduced in the late 1990s, CXL marked the first effective …

The meaning of the demarcation line after riboflavin-UVA corneal collagen crosslinking

C Mazzotta, G Wollensak, F Raiskup… - Expert review of …, 2019 - Taylor & Francis
Introduction: The demarcation line (DL) observed since the pioneering crosslink (CLX)
protocol at the posterior edge of the cross-linked stroma has been universally accepted as a …

The role of corneal biomechanics for the evaluation of ectasia patients

MQ Salomão, AL Hofling-Lima… - International Journal of …, 2020 - mdpi.com
Purpose: To review the role of corneal biomechanics for the clinical evaluation of patients
with ectatic corneal diseases. Methods: A total of 1295 eyes were included for analysis in …

Keratoconus detection of changes using deep learning of colour-coded maps

X Chen, J Zhao, KC Iselin, D Borroni… - BMJ Open …, 2021 - bmjophth.bmj.com
Objective To evaluate the accuracy of convolutional neural networks technique (CNN) in
detecting keratoconus using colour-coded corneal maps obtained by a Scheimpflug camera …

Development of a classification system based on corneal biomechanical properties using artificial intelligence predicting keratoconus severity

R Herber, LE Pillunat, F Raiskup - Eye and Vision, 2021 - Springer
Background To investigate machine-learning (ML) algorithms to differentiate corneal
biomechanical properties between different topographical stages of keratoconus (KC) by …

Corneal biomechanical outcome of collagen cross-linking in keratoconic patients evaluated by Corvis ST

M Jabbarvand, Z Moravvej, K Shahraki… - European Journal …, 2021 - journals.sagepub.com
Purpose: A 6-month evaluation of the topographic and biomechanical changes induced by
corneal collagen cross-linking (CXL) in keratoconic eyes using Pentacam and Corvis ST …

Evaluation of biomechanical changes after accelerated cross-linking in progressive keratoconus: a prospective follow-up study

R Herber, M Francis, E Spoerl, LE Pillunat, F Raiskup… - Cornea, 2023 - journals.lww.com
Purpose: The aim of this study was to analyze the biomechanical effect of accelerated
corneal cross-linking (9* 10) in progressive keratoconus (KC) in comparison to untreated …

Association between corneal stiffness parameter at the first applanation and keratoconus severity

K Yang, L Xu, Q Fan, S Ren - Journal of ophthalmology, 2020 - Wiley Online Library
Objective. The study aimed to evaluate the character of corneal stiffness parameter at the
first applanation (SP‐A1) in normal and keratoconus eyes and explore the association …

Comparison of waveform-derived corneal stiffness and stress-strain extensometry-derived corneal stiffness using different cross-linking irradiances: an experimental …

R Herber, M Francis, E Spoerl, LE Pillunat… - Graefe's Archive for …, 2020 - Springer
Purpose To assess corneal stiffening of standard (S-CXL) and accelerated (A-CXL) cross-
linking protocols by dynamic corneal response parameters and corneal bending stiffness …

Repeatability of corneal deformation response parameters by dynamic ultra–high-speed Scheimpflug imaging before and after corneal crosslinking

R Herber, R Vinciguerra, C Tredici… - Journal of Cataract & …, 2023 - journals.lww.com
Purpose: To evaluate the repeatability of deformation corneal response (DCR) parameters
before and after corneal crosslinking (CXL) compared with their untreated fellow eyes …