Brain tissue is not only one of the most important but also the most complex and compliant
tissue in the human body. While long underestimated, increasing evidence confirms that …

Brain aging is a complex process that affects everything from the subcellular to the organ
level, begins early in life, and accelerates with age. Morphologically, brain aging is primarily …

This monograph presents a general mathematical theory for biological growth. It provides
both a conceptual and a technical foundation for the understanding and analysis of …

Constitutive modeling is the cornerstone of computational and structural mechanics. In a
finite element analysis, the constitutive model is encoded in the material subroutine, a …

The rheology of ultrasoft materials like the human brain is highly sensitive to regional and
temporal variations and to the type of loading. While recent experiments have shaped our …

Convolutions are a classical hallmark of most mammalian brains. Brain surface morphology
is often associated with intelligence and closely correlated with neurological dysfunction …

Cerebral atrophy in response to traumatic brain injury is a well-documented phenomenon in
both primary investigations and review articles. Recent atrophy studies focus on exploring …

The prion hypothesis states that misfolded proteins can act as infectious agents that
template the misfolding and aggregation of healthy proteins to transmit a disease. Increasing …

Emerging evidence suggests that the mechanical behavior of the brain plays a critical role in
development, disease, and aging. Recent studies have begun to characterize the …

Soft materials play an integral part in many aspects of modern life including autonomy,
sustainability, and human health, and their accurate modeling is critical to understand their …