Responsible innovation requires that scientific and other expert practices be responsive to
society. We take stock of various collaborative approaches to socio-technical integration that …

The Human Genome Project (HGP) is often described as the first large-scale scientific
project to incorporate investigation of its own ethical and social dimensions into the “core” …

Vaccinomics is the convergence of vaccinology and population-based omics sciences. The
success of knowledge-based innovations such as vaccinomics is not only contingent on …

“Because DNA sequencing technology is inherently simpler and more scalable than protein
analytical technology, and because the finiteness of genomes invited a spirit of rapid …

''Both in research and policy I have emphasized the circumstances in which people are born,
grow, live, work, and age. These all loom larger as causes of health inequalities than defects …

Postgenomics personalized medicine science is experiencing a “data deluge” from
emerging high-throughput technologies and a myriad of sensors and exponential growth in …

A grand challenge for twenty-first-century medicine is to understand how knowledge about
human genomic variation and its interaction with the environment can be used, across the …

Membrane transporters such as P-glycoprotein (P-gp) and breast cancer resistance protein
(BCRP) are efflux pumps that remove drugs from the brain back to the peripheral blood …

All too frequently… a risk information vacuum interposes itself between experts and the
public, blocking the exchanges that ought to be occurring regularly. Trapped in the resulting …