The malignant tumor is a multi-etiological, systemic and complex disease characterized by
uncontrolled cell proliferation and distant metastasis. Anticancer treatments including …

Extracellular matrix (ECM) is a dynamic 3‐dimensional network of macromolecules that
provides structural support for the cells and tissues. Accumulated knowledge clearly …

The existence of orderly structures, such as tissues and organs is made possible by cell
adhesion, ie, the process by which cells attach to neighbouring cells and a supporting …

Hyaluronan (HA) is a critical element of the extracellular matrix (ECM). The regulated
synthesis and degradation of HA modulates the ECM chemical and physical properties that …

Abstract Rationale: Extracellular vesicles (EVs) from mesenchymal stromal cell (MSC) are a
potential therapy for cardiac healing after myocardial infarction (MI). Nevertheless, neither …

Bone organoids, which simulate and construct special organs in vitro with complex
biological functions based on tissue engineering technology, provide dramatically realistic …

The cornea and the skin are two organs that form the outer barrier of the human body. When
either is injured (eg, from surgery, physical trauma, or chemical burns), wound healing is …

Hyaluronan (HA) is a linear glycosaminoglycan (GAG) of extracellular matrix (ECM)
synthesized by three hyaluronan synthases (HASes) at the plasma membrane using uridine …

Simple Summary Extracellular matrix is a three-dimensional network of macromolecules that
provide structural and biochemical support to surrounding cells. Extracellular matrix plays a …

Cathepsins encompass a family of lysosomal proteases that mediate protein degradation
and turnover. Although mainly localized in the endolysosomal compartment, cathepsins are …