Objective: To develop a clinical practice guideline for red blood cell transfusion in adult
trauma and critical care. Design: Meetings, teleconferences and electronic-based …

Modalities of fluid management in patients sustaining the acute respiratory distress
syndrome (ARDS) are challenging and controversial. Optimal fluid management should …

Objective: We sought to develop an intensive care unit research database applying
automated techniques to aggregate high-resolution diagnostic and therapeutic data from a …

Massive transfusion (MT) is a lifesaving treatment of hemorrhagic shock, but can be
associated with significant complications. The lethal triad of acidosis, hypothermia, and …

Background: The relationship between body mass index (BMI) and development of acute
respiratory distress syndrome (ARDS) is unknown. Methods: A cohort study of critically ill …

Objective: Fluid overload has been independently associated with increased morbidity and
mortality in pediatric patients with renal failure, acute lung injury, and sepsis. Pediatric …

BACKGROUND: For trauma patients requiring massive blood transfusion, aggressive
plasma usage has been demonstrated to confer a survival advantage. The aim of this study …

Background Mechanical ventilation in intensive care for 48 h or longer is associated with the
acute respiratory distress syndrome (ARDS), which might be present at the time ventilatory …

Objectives: Breath-stacking asynchrony during assist-control-mode ventilation may be
associated with increased tidal volume and alveolar pressure that could contribute to …

We conducted an observational prospective multicenter study to describe the practices of
mechanical ventilation, to determine the incidence of use of large intra‐operative tidal …