Background Artesunate, as a semi-synthetic artemisinin derivative of sesquiterpene lactone,
is widely used in clinical antimalarial treatment due to its endoperoxide group. Recent …

Artemisinin-based combination therapy (ACT) is the recommended first-line treatment for
Plasmodium falciparum malaria. It has been suggested that the cytotoxic effect of artemisinin …

Background Artesunate (ART) is an artemisinin derivative used as monotherapy for the
treatment of severe malaria and in combination with a partner drug for non-severe malaria …

We have tested five distinct classes of established and experimental antimalarial drugs for
their anticancer potential, using a panel of 91 human cancer lines. Three classes of drugs …

As the toll of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic
continues, efforts are ongoing to identify new agents and repurpose safe drugs for its …

The anti-malaria drug Artesunate (ART) shows strong anti-cancer effects in vitro; however, it
shows only marginal treatment results in clinical cancer studies. In this study, ART was …

An antimalarial medication, artesunate (Art), has exhibited promising anticancer effects with
excellent tolerability in various types of cancer, suggesting that it has the potential to be used …

Background: Ovarian cancer is the deadliest gynecologic malignancy despite current first-
line treatment with a platinum and taxane doublet. Artesunate has broad antineoplastic …

Purpose.: Without therapeutic intervention, corneal neovascularization rapidly compromises
visual acuity, and is a leading cause of blindness. Artesunate was reported to inhibit …

Parenteral artesunate (ARS) is the drug of choice for the treatment of severe malaria.
Pharmacokinetics data on intramuscular ARS are limited with respect to the main treatment …