In addition to the conventional chemotherapeutic drugs, potent inhibitors of key enzymes
that are differentially overexpressed in cancer cells and associated with its progression are …

Hydrogen sulfide (H2S) has emerged as a potent therapeutic agent with diverse
physiological functions, including vasodilation, anti-inflammation, and cytoprotection …

Hydrogen sulfide (H2S) serves as the third gasotransmitter, crucial in various physiological
processes involving its production and metabolism. Elevated levels of H2S can result in …

Boronates react directly and stoichiometrically with peroxynitrite and hydrogen peroxide. For
this reason, boronates have been widely used as peroxynitrite-and hydrogen peroxide …

Amonafide (ANF), a topoisomerase II inhibitor and DNA intercalator, has exhibited promise
in phase II trials but faces significant limitations due to adverse side effects. Here, we have …

Hydrogen sulfide (H2S) is considered the third member of the gasotransmitter family, along
with nitric oxide (NO) and carbon monoxide (CO). Besides its role in physiological and …

Leveraging the elevated hydrogen peroxide (H 2 O 2) levels in cancer cells, H 2 O 2-
activated prodrugs have emerged as promising candidates for anticancer therapy. Notably …

Photo‐triggered ROS‐responsive supramolecular nanoprodrugs (BNN6@ GBTC NPs) are
constructed via supramolecular self‐assembly of amphiphilic prodrug molecule (GBTC) and …

This chapter explores the cutting-edge field of prodrugs responding to reactive oxygen
species (ROS). The growing trend to exploit the dynamic redox conditions present in various …

Stimuli‐responsive prodrugs of anticancer drugs are advantageous for the selective delivery
of drugs to cancer cells with minimized off‐target side effects. In the present study, esterase …