Nutraceuticals and cancer: Potential for natural polyphenols

J Maiuolo, M Gliozzi, C Carresi, V Musolino… - Nutrients, 2021 - mdpi.com
Cancer is one of the leading causes of death globally, associated with multifactorial
pathophysiological components. In particular, genetic mutations, infection or inflammation …

Curcumin as an enhancer of therapeutic efficiency of chemotherapy drugs in breast cancer

R Farghadani, R Naidu - International Journal of Molecular Sciences, 2022 - mdpi.com
Female breast cancer is the world's most prevalent cancer in 2020. Chemotherapy still
remains a backbone in breast cancer therapy and is crucial in advanced and metastatic …

Receptor tyrosine kinases and their signaling pathways as therapeutic targets of curcumin in cancer

S Sudhesh Dev, SA Zainal Abidin… - Frontiers in …, 2021 - frontiersin.org
Receptor tyrosine kinases (RTKs) are transmembrane cell-surface proteins that act as signal
transducers. They regulate essential cellular processes like proliferation, apoptosis …

Curcumin and plumbagin synergistically target the PI3K/Akt/mTOR pathway: a prospective role in cancer treatment

I Ahmad, M Hoque, SSM Alam, TA Zughaibi… - International journal of …, 2023 - mdpi.com
Cancer development is associated with the deregulation of various cell signaling pathways
brought on by certain genetic and epigenetic alterations. Therefore, novel therapeutic …

New insights into curcumin-and resveratrol-mediated anti-cancer effects

A Arena, MA Romeo, R Benedetti, L Masuelli, R Bei… - Pharmaceuticals, 2021 - mdpi.com
Curcumin and resveratrol are bioactive natural compounds displaying anti-inflammatory,
anti-oxidant and anti-cancer properties. In this study, we compared the cytotoxic effects of …

Antitumor properties of curcumin in breast cancer based on preclinical studies: a systematic review

KA Barcelos, CR Mendonça, M Noll, AF Botelho… - Cancers, 2022 - mdpi.com
Simple Summary Natural formulations and phytotherapies have shown promising antitumor
activities. This review assesses the antitumor effects of curcumin on breast cancer. In …

Nanoparticulate drugs and vaccines: breakthroughs and bottlenecks of repurposing in breast cancer

P Kumbhar, K Kole, V Khadake, P Marale… - Journal of Controlled …, 2022 - Elsevier
Breast cancer (BC) is a highly diagnosed and topmost cause of death in females worldwide.
Drug repurposing (DR) has shown great potential against BC by overcoming major …

Nano-based formulations of curcumin: Elucidating the potential benefits and future prospects in skin cancer

C Ratan, AM Arian, R Rajendran… - Biomedical …, 2023 - iopscience.iop.org
Skin cancer refers to any malignant lesions that occur in the skin and are observed
predominantly in populations of European descent. Conventional treatment modalities such …

Folic acid-conjugated cancer drug curcumin-loaded albumin nanoparticles: Investigation of curcumin release kinetics

E Türkeş, YS Açıkel - Journal of Drug Delivery Science and Technology, 2024 - Elsevier
The aim of this study is to design a drug delivery system in which both the carrier material
and the flavonoid anticancer, chemopreventive and chemotherapeutic active substance to …

Recent advances in curcumin-loaded biomimetic nanomedicines for targeted therapies

F Lei, P Li, T Chen, Q Wang, C Wang, Y Liu… - Journal of Drug Delivery …, 2023 - Elsevier
Curcumin shows excellent anti-inflammatory and anti-tumor activities, but its solubility,
stability, and bioavailability are poor. Nanoparticle delivery systems can be used to enhance …