Mesenchymal stem cells for neurological disorders

A Andrzejewska, S Dabrowska, B Lukomska… - Advanced …, 2021 - Wiley Online Library
Neurological disorders are becoming a growing burden as society ages, and there is a
compelling need to address this spiraling problem. Stem cell‐based regenerative medicine …

[HTML][HTML] Natural medicine in neuroprotection for ischemic stroke: Challenges and prospective

T Tao, M Liu, M Chen, Y Luo, C Wang, T Xu… - Pharmacology & …, 2020 - Elsevier
There is a growing interest in using natural medicines to treat stroke as the leading cause of
disability worldwide. Especially plant-derived natural medicines have multiple beneficial …

[HTML][HTML] Neuroinflammation as a target for treatment of stroke using mesenchymal stem cells and extracellular vesicles

S Dabrowska, A Andrzejewska, B Lukomska… - Journal of …, 2019 - Springer
Ischemic stroke is the third cause of death in the developed countries and the main reason
of severe disability. Brain ischemia leads to the production of damage-associated molecular …

Insight into crosstalk between ferroptosis and necroptosis: novel therapeutics in ischemic stroke

Y Zhou, J Liao, Z Mei, X Liu, J Ge - Oxidative Medicine and …, 2021 - Wiley Online Library
Ferroptosis is a nonapoptotic form of cell death characterized by iron‐dependent
accumulation of lipid hydroperoxides to lethal levels. Necroptosis, an alternative form of …

[HTML][HTML] Hemorrhagic transformation after ischemic stroke: mechanisms and management

JM Hong, DS Kim, M Kim - Frontiers in Neurology, 2021 - frontiersin.org
Symptomatic hemorrhagic transformation (HT) is one of the complications most likely to lead
to death in patients with acute ischemic stroke. HT after acute ischemic stroke is diagnosed …

Advances in meningeal immunity

R Rua, DB McGavern - Trends in molecular medicine, 2018 - cell.com
The central nervous system (CNS) is an immunologically specialized tissue protected by a
blood–brain barrier. The CNS parenchyma is enveloped by a series of overlapping …

MicroRNA-based therapeutics in central nervous system injuries

P Sun, DZ Liu, GC Jickling… - Journal of Cerebral …, 2018 - journals.sagepub.com
Central nervous system (CNS) injuries, such as stroke, traumatic brain injury (TBI) and
spinal cord injury (SCI), are important causes of death and long-term disability worldwide …

[HTML][HTML] A review for the neuroprotective effects of andrographolide in the central nervous system

J Lu, Y Ma, J Wu, H Huang, X Wang, Z Chen… - Biomedicine & …, 2019 - Elsevier
Andrographolide is compound extracted from Andrographis paniculata (A. paniculata), a
traditional herb that has been used in ancient China and other parts of eastern Asia to treat …

[HTML][HTML] Mesenchymal stem cell-based therapy for stroke: current understanding and challenges

W Li, L Shi, B Hu, Y Hong, H Zhang, X Li… - Frontiers in Cellular …, 2021 - frontiersin.org
Stroke, the most prevalent cerebrovascular disease, causes serious loss of neurological
function and is the leading cause of morbidity and mortality worldwide. Despite advances in …

Ultrasmall iron‐gallic acid coordination polymer nanodots with antioxidative neuroprotection for PET/MR imaging‐guided ischemia stroke therapy

Y Du, Y Huo, Q Yang, Z Han, L Hou, B Cui, K Fan… - …, 2023 - Wiley Online Library
Oxidative stress from reactive oxygen species (ROS) is a reperfusion injury factor that can
lead to cell damage and death. Here, ultrasmall iron‐gallic acid coordination polymer …