Abstract The 1, 2, 3-triazole ring is a major pharmacophore system among nitrogen-
containing heterocycles. These five-membered heterocyclic motifs with three nitrogen …

Traditional organic antimicrobials mainly act on specific biochemical processes such as
replication, transcription and translation. However, the emergence and wide spread of …

There is a dire need for new antimicrobial compounds to combat the growing threat of
widespread antibiotic resistance. With a currently very scarce drug pipeline, consisting …

The antimicrobial resistance (AMR) is an intractable problem for the world. Metal ions are
essential for the cell process and biological function in microorganisms. Many metal-based …

Tuberculosis, a disease of poverty is a communicable infection with a reasonably high
mortality rate worldwide. 10 Million new cases of TB were reported with approx 1.4 million …

Metal-based drugs are privileged motifs that act as primary pharmacophores in bioactive
compounds for various diseases, including tuberculosis (TB). This potentially life-threatening …

Abstract A series of (E)-N-2 (5H)-furanonyl sulfonyl hydrazone derivatives have been
rationally designed and efficiently synthesized by one-pot reaction with good yields for the …

The newly emerged severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) cause
life‐threatening diseases in millions of people worldwide, in particular, in patients with …

Thiazole, triazole, thio and semicarbazones are privileged motifs that act as
pharmacophores in bioactive compounds for various diseases, such as Tuberculosis (TB) …

Novel multicomponent crystal forms were obtained from reactions of trans-disubstituted
cyclam derivatives with flufenamic and salicylic acids. The reactions of H2 (4-CF3PhCH2) …