Langerhans cell histiocytosis (LCH) is an inflammatory neoplasia of myeloid precursor cells
driven by mutations in the mitogen-activated protein kinase pathway. When disease involves …

Head and neck (H&N) malignancies are rare in pediatric patients, and represent 12% of all
pediatric malignancies. 1 The incidence of these H&N tumors is 1.49 cases per 1,000,000 …

目的: 总结首发于鼻颅底的朗格汉斯细胞增生症(LCH) 的临床特点, 探讨其诊断及治疗方案.
方法: 回顾性分析以鼻颅底症状为首发表现的10 例LCH 患儿的资料, 总结其鼻部及颅底症状的 …

Langerhans cell histiocytosis (LCH) is a diagnostic and therapeutic challenge. We report on
a rare case of its primary oral manifestation that was treated successfully with the BRAF …

Langerhans cell histiocytosis (LCH) is the latest terminology for a disorder of reticulo-
endothelial system, previously known as histiocytosis X, and marked by aberrant …

Oral manifestations may be the first sign of Langerhans Cell Histiocytosis. Due to diversity in
the clinical findings of LCH, this disease has been a diagnostic dilemma to the clinicians …

Background: Langerhans cell histiocytosis (LCH) is a poorly understood disease with
heterogeneous clinical presentation ranging from unifocal bony involvement to …

Histocytóza z Langerhansových buněk (Langerhans cell histiocytosis–LCH) je velmi vzácné
onemocnění postihující jedince obou pohlaví jakéhokoliv věku. Často má formu …

Background. Langerhans cell histiocytosis is a rare reactive proliferative disorder marked by
excess proliferation and accumulation of mononuclear phagocytes in tissues and organs …

Objective: To summarize the clinical features, diagnosis and treatment of Langerhans
histiocytosis (LCH) which first appeared in the nasal skull base. Method: Ten cases of LCH …