Anxiety and stress disorders are the most commonly occurring of all mental illnesses, and
current treatments are less than satisfactory. So, the discovery of novel approaches to treat …

Movement, the fundamental component of behavior and the principal extrinsic action of the
brain, is produced when skeletal muscles contract and relax in response to patterns of action …

The modification of the discharge pattern of subthalamic nucleus (STN) neurons from single-
spike activity to mixed burst-firing mode is one of the characteristics of parkinsonism in rat …

Aging is a naturally occurring decline of physiological processes and biological pathways
that affects both the structural and functional integrity of the body and brain. These …

Shal-type (Kv4. x) K+ channels are expressed in a variety of tissue, with particularly high
levels in the brain and heart. These channels are the primary subunits that contribute to …

Inhibition of" leak" potassium (K+) channels is a widespread CNS mechanism by which
transmitters induce slow excitation. We show that TASK-1, a two pore domain K+ channel …

Oxytocin secretion from the posterior pituitary gland is increased during parturition,
stimulated by the uterine contractions that forcefully expel the fetuses. Since oxytocin …

Glutamate is the major excitatory neurotransmitter in the brain and plays a unique role in a
variety of central nervous system (CNS) functions. The discovery of the metabotropic …

Oxytocin-secreting neurons of the hypothalamoneurohypophysial system undergo
reversible morphological changes whenever they are strongly stimulated. In the …

Leak K+ currents contribute to the resting membrane potential and are important for
modulation of neuronal excitability. Within the past few years, an entire family of genes has …