Phytocannabinoids in the pharmacotherapy of psoriasis
A Wroński, I Jarocka-Karpowicz, A Stasiewicz… - Molecules, 2023 - mdpi.com
Phytocannabinoids are naturally occurring compounds, the main source of which is
Cannabis sativa L. Through direct action or interaction with G protein-coupled receptors …
Cannabis sativa L. Through direct action or interaction with G protein-coupled receptors …
Inhibition of keratinocyte ferroptosis suppresses psoriatic inflammation
Y Shou, L Yang, Y Yang, J Xu - Cell death & disease, 2021 - nature.com
Psoriasis is a common, chronic, and recurrent inflammatory disease. It is characterized by
hyperproliferation and abnormal differentiation of keratinocytes. Keratinocyte death is also …
hyperproliferation and abnormal differentiation of keratinocytes. Keratinocyte death is also …
Potential role of cytochrome c and tryptase in psoriasis and psoriatic arthritis pathogenesis: focus on resistance to apoptosis and oxidative stress
MS Chimenti, F Sunzini, L Fiorucci, E Botti… - Frontiers in …, 2018 - frontiersin.org
Psoriasis (PsO) is an autoimmune disease characterized by keratinocyte proliferation,
chronic inflammation and mast cell activation. Up to 42% of patients with PsO may present …
chronic inflammation and mast cell activation. Up to 42% of patients with PsO may present …
The antimicrobial peptide LL37 is a T-cell autoantigen in psoriasis
R Lande, E Botti, C Jandus, D Dojcinovic… - Nature …, 2014 - nature.com
Psoriasis is a common T-cell-mediated skin disease with 2–3% prevalence worldwide.
Psoriasis is considered to be an autoimmune disease, but the precise nature of the …
Psoriasis is considered to be an autoimmune disease, but the precise nature of the …
Evidence of pyroptosis and ferroptosis extensively involved in autoimmune diseases at the single-cell transcriptome level
D Zhang, Y Li, C Du, L Sang, L Liu, Y Li, F Wang… - Journal of Translational …, 2022 - Springer
Abstract Background Approximately 8–9% of the world's population is affected by
autoimmune diseases, and yet the mechanism of autoimmunity trigger is largely …
autoimmune diseases, and yet the mechanism of autoimmunity trigger is largely …
[HTML][HTML] Daphnetin inhibits proliferation and inflammatory response in human HaCaT keratinocytes and ameliorates imiquimod-induced psoriasis-like skin lesion in …
J Gao, F Chen, H Fang, J Mi, Q Qi, M Yang - Biological Research, 2020 - SciELO Chile
GAO, Jintao et al. Daphnetin inhibits proliferation and inflammatory response in human
HaCaT keratinocytes and ameliorates imiquimod-induced psoriasis-like skin lesion in mice …
HaCaT keratinocytes and ameliorates imiquimod-induced psoriasis-like skin lesion in mice …
NAMPT-derived NAD+ fuels PARP1 to promote skin inflammation through parthanatos cell death
FJ Martínez-Morcillo, J Cantón-Sandoval… - PLoS …, 2021 - journals.plos.org
Several studies have revealed a correlation between chronic inflammation and nicotinamide
adenine dinucleotide (NAD+) metabolism, but the precise mechanism involved is unknown …
adenine dinucleotide (NAD+) metabolism, but the precise mechanism involved is unknown …
Etiopathogenesis of Psoriasis: Integration of Proposed Theories
BF Hernandez-Nicols, JJ Robledo-Pulido… - Immunological …, 2024 - Taylor & Francis
Psoriasis is a chronic inflammatory disease characterized by squamous and erythematous
plaques on the skin and the involvement of the immune system. Global prevalence for …
plaques on the skin and the involvement of the immune system. Global prevalence for …
Identification of new [1, 2, 4] triazolo [4, 3-a] quinoxalines as potent VEGFR-2 tyrosine kinase inhibitors: Design, synthesis, anticancer evaluation, and in silico studies
Tumor angiogenesis is mainly regulated by VEGFR-2. In this study, a new series of [1, 2, 4]
triazolo [4, 3-a] quinoxaline based-derivatives has been designed and synthesized to …
triazolo [4, 3-a] quinoxaline based-derivatives has been designed and synthesized to …
Elevated IL-22 in psoriasis plays an anti-apoptotic role in keratinocytes through mediating Bcl-xL/Bax
B Wang, D Han, F Li, W Hou, L Wang, L Meng, K Mou… - Apoptosis, 2020 - Springer
IL-22 is known to mediate inflammation in psoriasis, while IL-22 binding protein (IL-22BP)
binds IL-22 to suppress IL-22 signaling. However, the function of IL-22 in regulating …
binds IL-22 to suppress IL-22 signaling. However, the function of IL-22 in regulating …