Pericytes are vascular mural cells embedded in the basement membrane of blood
microvessels. They extend their processes along capillaries, pre-capillary arterioles and …

Pericytes, the mural cells of blood microvessels, have recently come into focus as regulators
of vascular morphogenesis and function during development, cardiovascular homeostasis …

The precise regulation of cerebral blood flow is critical for normal brain function, and its
disruption underlies many neuropathologies. The extent to which smooth muscle-covered …

The CLDN5 gene encodes claudin-5 (CLDN-5) that is expressed in endothelial cells and
forms tight junctions which limit the passive diffusions of ions and solutes. The blood–brain …

The blood-retinal barrier (BRB) regulates transport across retinal capillaries maintaining
proper neural homeostasis and protecting the neural tissue from potential blood borne …

The blood–retinal barrier (BRB) consists of tightly interconnected capillary endothelial cells
covered with pericytes and glia, but the role of the pericytes in BRB regulation is not fully …

The maturation of nascent vasculature, formed by vasculogenesis or angiogenesis, requires
recruitment of mural cells, generation of an extracellular matrix and specialization of the …

Intraventricular hemorrhage (IVH) is a major complication of prematurity. IVH typically
initiates in the germinal matrix, which is a richly vascularized collection of neuronal-glial …

Angiogenesis, the growth of blood vessels, is a fundamental biological process that controls
embryonic development and is also involved in numerous life-threatening human diseases …

Interactions between endothelial cells and mural cells (pericytes and vascular smooth
muscle cells) in the blood vessel wall have recently come into focus as central processes in …