The greater wax moth Galleria mellonella is an invertebrate that is increasingly being used
in scientific research. Its ease of reproduction, numerous offspring, short development cycle …

An overview of pyrroles as distinct scaffolds with therapeutic potential and the significance of
pyrrole derivatives for drug development are provided in this article. It lists instances of …

Growing global demand for new molecules to treat tuberculosis has created an urgent need
to develop novel strategies to combat the menace. BM212 related compounds were found to …

An exploration of the chemical space around a 2, 5-dimethylpyrrole scaffold of antitubercular
hit compound 1 has led to the identification of new derivatives active against Mycobacterium …

Type 2 diabetes mellitus is a chronic progressive disease that usually requires
polypharmacological treatment approaches. Previously we have described a series of 2 …

Pyrrole is a heterocyclic structure with diverse pharmacophores, enabling the creation of an
extensive lead molecule library. Its broad range of pharmacological profiles has concerned …

Pyrrole is one of the most widely used heterocycles in the pharmaceutical industry. Due to
the importance of pyrrole structure in drug design and development, herein, we tried to …

A new class of amphiphilic molecules, the lipoguanidines, designed as hybrids of guanidine
and fatty acid compounds, has been synthesized and developed. The new molecules …

Tumor progression depends on angiogenesis, which is stimulated by growth factors like
VEGF, targeting VEGFR kinase with small molecules is an effective anti‐angiogenic …

A series of pyrrole‐thiazolidin‐4‐one conjugates were synthesized and evaluated for their
anti‐mycobacterial and anti‐bacterial activities. Two compounds, 10 a and 10 k, were the …