Aging is among the most important risk factors for morbidity and mortality. To contribute
toward a molecular understanding of aging, we analyzed age-resolved transcriptomic data …

The proteostasis network (PN) regulates protein synthesis, folding, and degradation and is
critical for the health and function of all cells. The PN has been extensively studied in the …

Population Genetics and Microevolutionary Theory Explore the fundamentals of the
biological implications of population genetic theory In the newly revised Second Edition of …

Aging is a risk factor for a number of diseases, being the more notorious ones perhaps
neurodegenerative diseases such as Alzheimer's and Parkinson's. These and other age …

Pheromones exchanged by conspecifics are a major class of chemical signals that can alter
behavior, physiology, and development. In particular, males and females communicate with …

Ageing and sexual selection are intimately linked. There is by now compelling evidence
from studies performed across diverse organisms that males allocating resources to mating …

Classical evolutionary theories propose tradeoffs among reproduction, damage repair and
lifespan. However, the specific role of the germline in shaping vertebrate aging remains …

Climates are changing rapidly, demanding equally rapid adaptation of natural populations.
Whether sexual selection can aid such adaptation is under debate; while sexual selection …

The function of germ cells in somatic growth and aging has been demonstrated in
invertebrate models but remains unclear in vertebrates. We demonstrated sex-dependent …

Maternal effect senescence, a decline in offspring viability with maternal age, has been
documented across diverse animals, but its mechanisms remain largely unknown. Here, we …