[HTML][HTML] From bench to bedside: Single-cell analysis for cancer immunotherapy
EF Davis-Marcisak, A Deshpande, GL Stein-O'Brien… - Cancer cell, 2021 - cell.com
Single-cell technologies are emerging as powerful tools for cancer research. These
technologies characterize the molecular state of each cell within a tumor, enabling new …
technologies characterize the molecular state of each cell within a tumor, enabling new …
[HTML][HTML] Single-cell biological network inference using a heterogeneous graph transformer
Single-cell multi-omics (scMulti-omics) allows the quantification of multiple modalities
simultaneously to capture the intricacy of complex molecular mechanisms and cellular …
simultaneously to capture the intricacy of complex molecular mechanisms and cellular …
Intricacies of single-cell multi-omics data integration
A wealth of single-cell protocols makes it possible to characterize different molecular layers
at unprecedented resolution. Integrating the resulting multimodal single-cell data to find cell …
at unprecedented resolution. Integrating the resulting multimodal single-cell data to find cell …
Single-cell RNA analysis reveals the potential risk of organ-specific cell types vulnerable to SARS-CoV-2 infections
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global
pandemic of coronavirus disease 2019 (COVID-19) since December 2019 that has led to …
pandemic of coronavirus disease 2019 (COVID-19) since December 2019 that has led to …
[HTML][HTML] scREAD: a single-cell RNA-Seq database for Alzheimer's disease
Alzheimer's disease (AD) is a progressive neurodegenerative disorder of the brain and the
most common form of dementia among the elderly. The single-cell RNA-sequencing (scRNA …
most common form of dementia among the elderly. The single-cell RNA-sequencing (scRNA …
[HTML][HTML] The use of single-cell multi-omics in immuno-oncology
Single-cell multi-omics (scMulti-omics) has brought transformative insights into immuno-
oncology, demonstrating success in describing novel immune subsets and defining …
oncology, demonstrating success in describing novel immune subsets and defining …
[HTML][HTML] DNA sequencing: an overview of solid-state and biological nanopore-based methods
MM Mohammadi, O Bavi - Biophysical reviews, 2022 - Springer
The field of sequencing is a topic of significant interest since its emergence and has become
increasingly important over time. Impressive achievements have been obtained in this field …
increasingly important over time. Impressive achievements have been obtained in this field …
[HTML][HTML] Analyzing modern biomolecules: the revolution of nucleic-acid sequencing–Review
G Dorado, S Gálvez, TE Rosales, VF Vásquez… - Biomolecules, 2021 - mdpi.com
Recent developments have revolutionized the study of biomolecules. Among them are
molecular markers, amplification and sequencing of nucleic acids. The latter is classified into …
molecular markers, amplification and sequencing of nucleic acids. The latter is classified into …
Network biology bridges the gaps between quantitative genetics and multi-omics to map complex diseases
With advances in high-throughput sequencing technologies, quantitative genetics
approaches have provided insights into genetic basis of many complex diseases. Emerging …
approaches have provided insights into genetic basis of many complex diseases. Emerging …
[HTML][HTML] Integration and gene co-expression network analysis of scRNA-seq transcriptomes reveal heterogeneity and key functional genes in human spermatogenesis
Spermatogenesis is a complex process of cellular division and differentiation that begins
with spermatogonia stem cells and leads to functional spermatozoa production. However …
with spermatogonia stem cells and leads to functional spermatozoa production. However …