Metformin is the first-line antidiabetic drug and one of the most prescribed medications
worldwide. Because of its ubiquitous occurrence in global waters and demonstrated …

Metformin (MET) is the most common drug used to treat type 2 diabetes, but also it is used
as an anticancer agent and as a treatment for polycystic ovary syndrome. This drug is not …

The antidiabetic drug metformin (MET) and its metabolite guanylurea (GUA) have been
frequently and ubiquitously detected in surface water. Consequently, there has been a …

Metformin (MET), a worldwide used drug for type 2 diabetes, has been found with the largest
amount by weight among all drugs in aquatic environment, including the drinking water …

Antibiotics are known to be key drivers of antibiotic resistance and antibiotic resistance gene
transmission. However, the contribution of the emerging pollutant metformin in facilitating …

Metformin is one the most prescribed drug to treat type 2 diabetes. In wastewater treatment
plants, this drug is bacterially transformed to guanylurea, which occurs at higher …

Human-use pharmaceuticals in urban streams link aquatic-ecosystem health to human
health. Pharmaceutical mixtures have been widely reported in larger streams due to …

Microplastics (MPs) alone may endanger the health and fitness of aquatic species through
different mechanisms. However, the harmful effects of these when mixed with other …

Global demand for safe and sustainable water supplies necessitates a better understanding
of contaminant exposures in potential reuse waters. In this study, we compared exposures …

Recent studies have shown guanylurea (GUA) alters the growth and development of fish,
induces oxidative stress, and disrupts the levels and expression of several genes …