Glia Development and Function in the Nematode Caenorhabditis elegans

A Singhvi, S Shaham, G Rapti - Cold Spring Harbor …, 2024 - cshperspectives.cshlp.org
The nematode Caenorhabditis elegans is a powerful experimental setting for uncovering
fundamental tenets of nervous system organization and function. Its nearly invariant and …

Aromatherapy with inhalation can effectively improve the anxiety and depression of cancer patients: A meta-analysis

T Liu, H Cheng, L Tian, Y Zhang, S Wang… - General Hospital …, 2022 - Elsevier
Purpose This meta-analysis was to critically evaluate the effects of aromatherapy on the
symptoms of anxiety and depression in cancer patients. Methods Eight Chinese and English …

Glial KCNQ K+ channels control neuronal output by regulating GABA release from glia in C. elegans

B Graziano, L Wang, OR White, DH Kaplan… - Neuron, 2024 - cell.com
KCNQs are voltage-gated K+ channels that control neuronal excitability and are mutated in
epilepsy and autism spectrum disorder (ASD). KCNQs have been extensively studied in …

Phasic/tonic glial GABA differentially transduce for olfactory adaptation and neuronal aging

H Cheng, D Chen, X Li, U Al-Sheikh, D Duan, Y Fan… - Neuron, 2024 - cell.com
Phasic (fast) and tonic (sustained) inhibition of γ-aminobutyric acid (GABA) are fundamental
for regulating day-to-day activities, neuronal excitability, and plasticity. However, the …

Functional Interaction Between Drosophila Olfactory Sensory Neurons and Their Support Cells

S Prelic, V Pal Mahadevan… - Frontiers in cellular …, 2022 - frontiersin.org
Insects detect volatile chemicals using antennae, which house a vast variety of olfactory
sensory neurons (OSNs) that innervate hair-like structures called sensilla where odor …

A glial ClC Cl− channel mediates nose touch responses in C. elegans

J Fernandez-Abascal, CK Johnson, B Graziano… - Neuron, 2022 - cell.com
In touch receptors, glia and accessory cells play a key role in mechanosensation. However,
the mechanisms underlying such regulation are poorly understood. We show, for the first …

[HTML][HTML] Neuron cilia restrain glial KCC-3 to a microdomain to regulate multisensory processing

S Ray, P Gurung, RS Manning, AA Kravchuk, A Singhvi - Cell Reports, 2024 - cell.com
Glia interact with multiple neurons, but it is unclear whether their interactions with each
neuron are different. Our interrogation at single-cell resolution reveals that a single glial cell …

Cilia structure and intraflagellar transport differentially regulate sensory response dynamics within and between C. elegans chemosensory neurons

A Philbrook, MP O'Donnell, L Grunenkovaite… - PLoS …, 2024 - journals.plos.org
Sensory neurons contain morphologically diverse primary cilia that are built by intraflagellar
transport (IFT) and house sensory signaling molecules. Since both ciliary structural and …

A neurotransmitter atlas of C. elegans males and hermaphrodites

C Wang, B Vidal, S Sural, C Loer, GR Aguilar… - Elife, 2024 - elifesciences.org
Mapping neurotransmitter identities to neurons is key to understanding information flow in a
nervous system. It also provides valuable entry points for studying the development and …

Behavioral plasticity

Y Zhang, Y Iino, WR Schafer - Genetics, 2024 - academic.oup.com
Behavioral plasticity allows animals to modulate their behavior based on experience and
environmental conditions. Caenorhabditis elegans exhibits experience-dependent changes …