[HTML][HTML] Haematopoietic Stem Cell Transplantation in Thalassaemia Major: A Narrative Review

R Yousuf, D Jahan, S Sinha… - Advances in Human …, 2023 - journals.lww.com
Thalassaemia constitutes an especially prevalent human monogenic illness caused by a
lack of synthesis of the α-or β-globin chains. The clinical impact of β-thalassaemia is worse …

Haploidentical hematopoietic stem cell transplantation in pediatric transfusion-dependent thalassemia: a systematic review and meta-analysis

H Xiao, Q Huang, R Liu, Y Lai - Transplantation and Cellular Therapy, 2024 - Elsevier
Background Haploidentical hematopoietic stem cell transplantation (haplo-HSCT) presents
a promising therapeutic option for pediatric transfusion-dependent thalassemia, particularly …

What we learn from surveillance of microbial colonization in recipients of pediatric hematopoietic stem cell transplantation

G Kropshofer, B Hetzer, M Knoll, A Meryk, C Salvador… - Antibiotics, 2022 - mdpi.com
Infections in hematopoietic stem cell transplant (HSCT) remain one of the major causes for
morbidity and mortality, and it is still unclear whether knowledge of microbial colonization is …

Finding a balance in reduced toxicity hematopoietic stem cell transplantation for thalassemia: role of infused CD3+ cell count and immunosuppression

B Meissner, P Lang, P Bader, M Hoenig… - Bone Marrow …, 2024 - nature.com
We performed a retrospective analysis on 124 patients with transfusion-dependent
thalassemia who were registered in the German pediatric registry for stem cell …

[HTML][HTML] A novel conditioning regimen with pre-transplantation immunosuppression reduces the complication rates in hematopoietic stem cell transplantation in …

H Yang, X Li, L Que, H Chen, L Zhan… - Stem Cell Research …, 2024 - pmc.ncbi.nlm.nih.gov
Background Allo-HSCT is a curative therapy for patients with transfusion-dependent
thalassemia (TDT). The high incidence of transplant-related complications is becoming an …

Haploidentical transplant for paediatric patients with severe thalassaemia using post‐transplant cyclophosphamide and methotrexate: A prospectively registered …

J Hu, S Gong, K Chen, R Yang, L Wang… - British Journal of …, 2023 - Wiley Online Library
Haploidentical transplantation strategies for patients with transfusion‐dependent
thalassaemia (TD‐TM) remain to be investigated. In this study, 54 paediatric patients with TD …

Prevalence and Clinical Features of Thalassemia Minor Cases

M Faizan, N Rashid, S Hussain, A Khan… - Pakistan Journal of …, 2023 - pjmhsonline.com
Background: Thalassemia, the most common heterogeneous single gene disorder causing
sever genetic health problem in the world. In 1932 George and William gave it the name …

Outcomes of Hematopoietic Stem Cell Transplantation in Patients With Thalassemia Major: How Do Anti‐HLA Antibodies Impact? The Impact of Anti‐HLA Antibodies …

GZ Ersoy, BA Aksoy, M Erdem, L Karataş… - Clinical …, 2024 - Wiley Online Library
Aim To investigate the effects of anti‐human Leucocyte Antigen (HLA) antibody positivity on
early hematopoietic stem cell transplantation (HSCT) results in patients with thalassemia …

Hematopoietic Stem Cell Transplantation in Children with Sickle Cell Disease and Thalassemia Major: A National Database Study: Stem Cell Transplantation for …

C De Avila, PA Martinez, P Sendi… - Pediatric Hematology …, 2024 - Taylor & Francis
In patients with sickle cell disease (SCD) and beta-thalassemia major (TM), allogeneic
hematopoietic stem cell transplantation (HSCT) was considered the only curative treatment …

Effect of serum panel reactive antibodies on allogeneic hematopoietic stem cell transplantation in pediatric thalassemia patients: A single‐center experience

B Malbora, H Sarbay, Z Dogusan… - Pediatric …, 2024 - Wiley Online Library
Background The aim of this study was to assess the impact of serum panel reactive
antibodies (PRA) on the outcomes of allogeneic hematopoietic stem cell transplantation …