Although several major progresses have been introduced in the field of bone regenerative
medicine during the years, current therapies, such as bone grafts, still have many limitations …

As life expectancy increases, malfunction or loss of tissue caused by injury or disease leads
to reduced quality of life in many patients at significant socioeconomic cost. Even though …

The endothelial cell (EC) is practically ubiquitous in the human body and forms the inner
cellular lining of the entire cardiovascular system. Following tissue injury, the …

Polycaprolactone (PCL) is one of the earliest, commercially available, synthetic polymers
characterized by a large set of biodegradation and mechanical properties that can be finely …

Conventional materials technology has yielded clear improvements in regenerative
medicine. Ideally, however, a replacement material should mimic the living tissue …

Interests in the use of biodegradable polymers as biomaterials have grown. Among the
different polymeric composites currently available, the blend of starch and polycaprolactone …

Tissue engineering (TE) offers a potential solution for the shortage of transplantable organs
and the need for novel methods of tissue repair. Methods of TE have advanced significantly …

In scaffold‐based tissue engineering strategies, the successful regeneration of tissues from
matrix‐producing connective tissue cells or anchorage‐dependent cells (eg osteoblasts) …

There is an increasing interest in developing novel macromolecular vehicles for the
intracellular and controlled delivery of bioactive molecules, since they can allow modulation …

Spinal cord injury (SCI) represents a significant health and social problem, and therefore it is
vital to develop novel strategies that can specifically target it. In this context, the objective of …