Infant BCG vaccination and risk of pulmonary and extrapulmonary tuberculosis throughout the life course: a systematic review and individual participant data meta …

L Martinez, O Cords, Q Liu… - The Lancet Global …, 2022 - thelancet.com
Background BCG vaccines are given to more than 100 million children every year, but there
is considerable debate regarding the effectiveness of BCG vaccination in preventing …

The risk of tuberculosis in children after close exposure: a systematic review and individual-participant meta-analysis

L Martinez, O Cords, CR Horsburgh, JR Andrews… - The Lancet, 2020 - thelancet.com
Background Tens of millions of children are exposed to Mycobacterium tuberculosis globally
every year; however, there are no contemporary estimates of the risk of developing …

[HTML][HTML] Childhood pneumonia in low-and-middle-income countries: An update

D Marangu, HJ Zar - Paediatric respiratory reviews, 2019 - Elsevier
Objectives To review epidemiology, aetiology and management of childhood pneumonia in
low-and-middle-income countries. Design Review of published English literature between …

Incidence and prevalence of tuberculosis in incarcerated populations: a systematic review and meta-analysis

O Cords, L Martinez, JL Warren, JM O'Marr… - The Lancet Public …, 2021 - thelancet.com
Background Prisons are recognised as high-risk environments for tuberculosis, but there
has been little systematic investigation of the global and regional incidence and prevalence …

Complicated pneumonia in children

FM de Benedictis, E Kerem, AB Chang, AA Colin… - The Lancet, 2020 - thelancet.com
Complicated community-acquired pneumonia in a previously well child is a severe illness
characterised by combinations of local complications (eg, parapneumonic effusion …

The long-term impact of early-life tuberculosis disease on child health: a prospective birth cohort study

L Martinez, DM Gray, M Botha, M Nel… - American Journal of …, 2023 - atsjournals.org
Rationale: There is growing concern that post–tuberculosis disease (TB) sequelae and
morbidity are substantial, but no studies have controlled for preexisting factors before …

Mycobacterium tuberculosis Transmission in High-Incidence Settings—New Paradigms and Insights

M Coleman, L Martinez, G Theron, R Wood, B Marais - Pathogens, 2022 - mdpi.com
Tuberculosis has affected humankind for thousands of years, but a deeper understanding of
its cause and transmission only arose after Robert Koch discovered Mycobacterium …

[HTML][HTML] The association between bacteria colonizing the upper respiratory tract and lower respiratory tract infection in young children: a systematic review and meta …

S Claassen-Weitz, KYL Lim, C Mullally, HJ Zar… - Clinical Microbiology …, 2021 - Elsevier
Background Bacteria colonizing the upper respiratory tract (URT) of young children play a
key role in the pathogenesis of lower respiratory tract infection (LRTI). Objectives To …

Cytomegalovirus acquisition in infancy and the risk of tuberculosis disease in childhood: a longitudinal birth cohort study in Cape Town, South Africa

L Martinez, MP Nicol, CJ Wedderburn… - The Lancet Global …, 2021 - thelancet.com
Background The risk of tuberculosis disease after recent exposure is greatest before age 5
years; however, the mechanisms explaining this increased risk are not well elucidated …

Paediatric tuberculosis transmission outside the household: challenging historical paradigms to inform future public health strategies

L Martinez, NC Lo, O Cords, PC Hill, P Khan… - The Lancet …, 2019 - thelancet.com
Tuberculosis is a major cause of death and disability among children globally, yet children
have been neglected in global tuberculosis control efforts. Historically, tuberculosis in …