Diabetic peripheral neuropathy (DPN) is a common complication of both type 1 and 2
diabetes. It is a leading cause of lower-limb amputation and disabling neuropathic pain …

Purpose Diabetic peripheral neuropathy (DPN) is the commonest cause of neuropathy
worldwide, and its prevalence increases with the duration of diabetes. It affects …

Objectives Fibromyalgia is a condition which exhibits chronic widespread pain with
neuropathic pain features and has a major impact on health-related quality of life. The …

Purpose.: To assess the diagnostic validity of a fully automated image analysis algorithm of
in vivo confocal microscopy images in quantifying corneal subbasal nerves to diagnose …

Objectives Corneal confocal microscopy (CCM) is a rapid, non-invasive, reproducible
technique that quantifies small nerve fibres. We have compared the diagnostic capability of …

There are potentially many ways of assessing diabetic peripheral neuropathy (DPN).
However, they do not fulfill US Food and Drug Administration (FDA) requirements in relation …

Cardiac autonomic neuropathy (CAN) is a major complication of type 1 and type 2 diabetes
mellitus (T1DM and T2DM). The increased morbidity, cardiovascular and all-cause mortality …

OBJECTIVE Corneal confocal microscopy is a novel diagnostic technique for the detection
of nerve damage and repair in a range of peripheral neuropathies, in particular diabetic …

Aims/hypothesis We aimed to develop an artificial intelligence (AI)-based deep learning
algorithm (DLA) applying attribution methods without image segmentation to corneal …

OBJECTIVE Quantitative assessment of small fiber damage is key to the early diagnosis and
assessment of progression or regression of diabetic sensorimotor polyneuropathy (DSPN) …