[HTML][HTML] Recent advances in electrochemiluminescence imaging analysis

C Meng, S Knežević, F Du, Y Guan, F Kanoufi, N Sojic… - EScience, 2022 - Elsevier
Electrochemiluminescence (ECL) has been widely applied in imaging owing to features that
distinguish it from other microscopic techniques and electrochemical methods, including its …

Clamping strategies for organ-on-a-chip devices

DJ Teixeira Carvalho, L Moroni… - Nature Reviews Materials, 2023 - nature.com
Organ-on-a-chip devices have enabled major breakthroughs in biomedical research, but
they have yet to be successfully translated to the pharmaceutical industry. Traditional …

Organ-on-a-chip platforms for drug screening and delivery in tumor cells: A systematic review

IM Gonçalves, V Carvalho, RO Rodrigues, D Pinho… - Cancers, 2022 - mdpi.com
Simple Summary Cancer is one of the diseases with a high mortality rate worldwide. Of the
current strategies to study new diagnostic and treating tools, organs-on-chip are quite …

Spheroid engineering in microfluidic devices

A Tevlek, S Kecili, OS Ozcelik, H Kulah, HC Tekin - ACS omega, 2023 - ACS Publications
Two-dimensional (2D) cell culture techniques are commonly employed to investigate
biophysical and biochemical cellular responses. However, these culture methods, having …

Implications of nanotechnology for the treatment of cancer: Recent advances

SG Klochkov, ME Neganova, VN Nikolenko… - Seminars in cancer …, 2021 - Elsevier
The use of nanoparticles dramatically increases the safety and efficacy of the most common
anticancer drugs. The main advantages of nano-drugs and delivery systems based on nano …

Recent trends of biomaterials and biosensors for organ-on-chip platforms

IM Gonçalves, RO Rodrigues, AS Moita, T Hori, H Kaji… - Bioprinting, 2022 - Elsevier
Abstract Organ-on-chip (OoC) platforms are a new class of advanced microfluidic devices
that have been attracting significant attention for drug development since they can allow a …

[HTML][HTML] The integration of spheroids and organoids into organ-on-a-chip platforms for tumour research: A review

V Carvalho, M Bañobre-López, G Minas, SFCF Teixeira… - Bioprinting, 2022 - Elsevier
Every year, cancer causes millions of deaths around the globe, and researchers have been
engaged to provide novel therapies for this threatening disease. However, this process is …

Thyroid‐on‐a‐Chip: An Organoid Platform for In Vitro Assessment of Endocrine Disruption

DJ Carvalho, AM Kip, M Romitti… - Advanced …, 2023 - Wiley Online Library
Thyroid is a glandular tissue in the human body in which the function can be severely
affected by endocrine disrupting chemicals (EDCs). Current in vitro assays to test endocrine …

Advanced drug delivery micro-and nanosystems for cardiovascular diseases

S Iravani, RS Varma - Molecules, 2022 - mdpi.com
Advanced drug delivery micro-and nanosystems have been widely explored due to their
appealing specificity/selectivity, biodegradability, biocompatibility, and low toxicity. They can …

Recent advances in three-dimensional multicellular spheroid culture and future development

H Shen, S Cai, C Wu, W Yang, H Yu, L Liu - Micromachines, 2021 - mdpi.com
Three-dimensional multicellular spheroids (MCSs) have received extensive attention in the
field of biomedicine due to their ability to simulate the structure and function of tissues in vivo …