Circadian regulation in aging: Implications for spaceflight and life on earth

D Malhan, B Schoenrock, M Yalçin, D Blottner… - Aging …, 2023 - Wiley Online Library
Alterations in the circadian system are characteristic of aging on Earth. With the decline in
physiological processes due to aging, several health concerns including vision loss …

[HTML][HTML] Conquering space with crops that produce ample oxygen and antioxidants

SK Polutchko, WW Adams, CM Escobar… - Oxygen, 2022 - mdpi.com
Sustainable long-term space missions require regenerative life support from plants.
Traditional crop plants lack some features desirable for use in space environments. The …

Biological and mechanical characterization of the random positioning machine (rpm) for microgravity simulations

M Calvaruso, C Militello, L Minafra, V La Regina… - Life, 2021 - mdpi.com
The rapid improvement of space technologies is leading to the continuous increase of space
missions that will soon bring humans back to the Moon and, in the coming future, toward …

Telomeres and aging: on and off the planet!

CE Mason, MA Sierra, HJ Feng, SM Bailey - Biogerontology, 2024 - Springer
Improving human healthspan in our rapidly aging population has never been more
imperative. Telomeres, protective “caps” at the ends of linear chromosomes, are essential for …

Telomeric RNA (TERRA) increases in response to spaceflight and high-altitude climbing

TM Al-Turki, DG Maranon, CB Nelson… - Communications …, 2024 - nature.com
Telomeres are repetitive nucleoprotein complexes at chromosomal termini essential for
maintaining genome stability. Telomeric RNA, or TERRA, is a previously presumed long …

[HTML][HTML] A preharvest finishing procedure for Lemna to produce high levels of zeaxanthin that is retained post-high-light exposure

M López-Pozo, WW Adams III, M McNamara… - Future Foods, 2024 - Elsevier
Abstract Development of a productive, nutritious, and low-input food source is needed for
humanity's expanding population on Earth and for long-duration crewed space missions …

Three decades of ethological research in the space field within an interdisciplinary framework

C Tafforin, N Kanas, FG Abati, C Tamponnet - Acta Astronautica, 2023 - Elsevier
In a wide panel of environments (space shuttles, orbital stations, parabolic flights, Arctic
expeditions, Antarctic bases) and experiments (ISEMSI, EXEMSI, HUBES, CELSS, MARS …

Telomere length dynamics associated with short-duration human spaceflight

B Shirah, EG Overbey, J Foox, JW Hirschberg… - … Research in Short …, 2025 - Elsevier
Introduction Telomeres, the protective “caps”'at the ends of linear chromosomes, are
essential for preserving genome stability. Although human telomeres naturally vary in length …

Women's health in spaceflight

S Puukila, JS Alwood, LK Christenson… - Precision Medicine for …, 2025 - Elsevier
Historically, only 75 women have flown in space, and while this inequity has been recently
addressed with astronaut candidates approximately 50% female, research defining female …

[HTML][HTML] Complementarity of NASA's Division of Biological and Physical Sciences and Human Research Program

SS Board, PSR in Space… - Thriving in Space …, 2023 - ncbi.nlm.nih.gov
This appendix references the scope of Chapter 4, and specifically the recognition that some
biological/life science research in the NASA Science Mission Directorate (SMD) Division of …