Hydrogel microparticles for biosensing

GC Le Goff, RL Srinivas, WA Hill, PS Doyle - European polymer journal, 2015 - Elsevier
Due to their hydrophilic, biocompatible, and highly tunable nature, hydrogel materials have
attracted strong interest in the recent years for numerous biotechnological applications. In …

Specificity of DNA microarray hybridization: characterization, effectors and approaches for data correction

H Koltai, C Weingarten-Baror - Nucleic acids research, 2008 - academic.oup.com
Microarray-hybridization specificity is one of the main effectors of microarray result quality. In
the present review, we suggest a definition for specificity that spans four hybridization levels …

Direct reverse transcription real-time PCR of viral RNA from saliva samples using hydrogel microparticles

EG Kifaro, MJ Kim, S Jung, JY Noh, CS Song… - BioChip Journal, 2022 - Springer
In recent decades “saliva” has emerged as an important non-invasive biofluid for diagnostic
purposes in both human and animal health sectors. However, with the rapid evolution of …

DNA microarrays in the clinic: infectious diseases

V Mikhailovich, D Gryadunov, A Kolchinsky… - …, 2008 - Wiley Online Library
We argue that the most‐promising area of clinical application of microarrays in the
foreseeable future is the diagnostics and monitoring of infectious diseases. Microarrays for …

Kinetics of hybridization on surface oligonucleotide microchips: theory, experiment, and comparison with hybridization on gel-based microchips

NV Sorokin, VR Chechetkin, SV Pan'kov… - Journal of …, 2006 - Taylor & Francis
The optimal design of oligonucleotide microchips and efficient discrimination between
perfect and mismatch duplexes strongly depend on the external transport of target DNA to …

Hydrogel Droplet Microarray for Genotyping Antimicrobial Resistance Determinants in Neisseria gonorrhoeae Isolates

B Shaskolskiy, I Kandinov, D Kravtsov, A Vinokurova… - Polymers, 2021 - mdpi.com
A multiplex assay based on a low-density hydrogel microarray was developed to identify
genomic substitutions in N. gonorrhoeae that determine resistance to the currently …

Routine human papillomavirus genotyping by DNA sequencing in community hospital laboratories

SH Lee, VS Vigliotti, JS Vigliotti, S Pappu - Infectious Agents and Cancer, 2007 - Springer
Background Human papillomavirus (HPV) genotyping is important for following up patients
with persistent HPV infection and for evaluation of prevention strategy for the individual …

Hydrodynamic-flow-enhanced rapid mixer for isothermal DNA hybridization kinetics analysis on digital microfluidics platform

M Li, C Dong, MK Law, Y Jia, PI Mak… - Sensors and Actuators B …, 2019 - Elsevier
DNA hybridization kinetics has been playing a critical role in molecular diagnostics for
binding discrimination, but its study on digital microfluidic (DMF) systems is ultimately …

The EIMB hydrogel microarray technology: thirty years later

DA Gryadunov, BL Shaskolskiy… - Acta Naturae …, 2018 - cyberleninka.ru
Biological microarrays (biochips) are analytical tools that can be used to implement complex
integrative genomic and proteomic approaches to the solution of problems of personalized …

[HTML][HTML] An Approach to Identifying Single-Nucleotide Mutations Using Noncovalent Associates of Gold Nanoparticles with Fluorescently Labeled Oligonucleotides

AV Epanchintseva, EA Gorbunova… - International Journal of …, 2024 - mdpi.com
Globally, widespread tuberculosis is one of the acute problems of healthcare. Drug-resistant
forms of tuberculosis require a personalized approach to treatment. Currently, rapid methods …