Cytokine storm syndrome (CSS) has generally been described as a collection of clinical
manifestations resulting from an overactivated immune system. Cytokine storms (CSs) are …

Programmed cell death is regulated by evolutionarily conserved pathways that play critical
roles in development and the immune response. A newly recognized pathway for …

A20 is an anti-inflammatory protein linked to multiple human diseases; however, the
mechanisms by which A20 prevents inflammatory disease are incompletely defined. We …

A20, also known as TNFAIP3, is a potent regulator of ubiquitin (Ub) dependent signals. A20
prevents multiple human diseases, indicating that the critical functions of this protein are …

Mild versus severe psoriasis is often distinguished by clinical measures such as the extent of
skin involvement or Psoriasis Area and Severity Index score, both of which use arbitrary …

Psoriatic arthritis (PsA) is a chronic inflammatory condition characterized by psoriasis,
synovitis, enthesitis, spondylitis, and the possible association with other extra-articular …

Background and Objectives: Psoriasis is an immune-mediated chronic inflammatory skin
disorder and commonly associated with highly noticeable erythematous, thickened and …

Octamer binding transcription factor-4 (Oct4), is highly expressed in stem cells and has
indispensable roles in pluripotency and cellular reprogramming. In contrast to other factors …

Ulcerative colitis (UC), an inflammatory disorder of the colon arises from dysregulated
immune response towards gut microbes. Transcription factor NFκB is a major regulatory …

Background. Psoriasis is an immune‐mediated chronic inflammatory skin disorder in which
the dysregulation of immune cells plays an important role in its development. Tumor …